| Identification | Back Directory | [Name]
FA-ALA-ARG-OH | [CAS]
76079-06-6 | [Synonyms]
FA-AR-OH
FA-Ala-arg
FA-ALA-ARG-OH
FA-ALA-ARG-OH USP/EP/BP
furylacryloylalanylarginine
3-(2-FURYL)ACRYLOYL-ALA-ARG-OH
3-(2-FURYL)-ACRYLOYL-ALA-ARG SALT
N-[3-(2-Furanyl)-1-oxo-2-propen-1-yl]-L-alanyl-L-arginine
L-Arginine, N-[3-(2-furanyl)-1-oxo-2-propen-1-yl]-L-alanyl-
(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2-[[(E)-3-(furan-2-yl)prop-2-enoyl]amino]propanoyl]amino]pentanoicaci
(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2-[[(E)-3-(furan-2-yl)prop-2-enoyl]amino]propanoyl]amino]pentanoic acid | [Molecular Formula]
C16H23N5O5 | [MDL Number]
MFCD00237632 | [MOL File]
76079-06-6.mol | [Molecular Weight]
365.38 |
| Hazard Information | Back Directory | [Uses]
FA-Ala-Arg is a dipeptide with furylacryloyl group. FA-Ala-Arg breaks down to produce arginine. While cell-surface Carboxypeptidase-D (CPD) also increases intracellular Arg, which is converted to nitric oxide (NO). FA-Ala-Arg enhances NO production in MCF-7 cells. FA-Ala-Arg also increases the cell survival of prolactin (PRL)-treated cells, PRL regulates CPD mRNA levels in cells[1]. | [References]
[1] Abdelmagid SA, et al. Prolactin and estrogen up-regulate carboxypeptidase-d to promote nitric oxide production and survival of mcf-7 breast cancer cells. Endocrinology. 2008 Oct;149(10):4821-8. DOI:10.1210/en.2008-0145 |
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