ChemicalBook--->CAS DataBase List--->762274-58-8

762274-58-8

762274-58-8 Structure

762274-58-8 Structure
IdentificationBack Directory
[Name]

Smac inhibitor 2
[CAS]

762274-58-8
[Synonyms]

A 410099.1
Smac inhibitor 2
BATZLZWUKSHCHR-HLJCKNCVSA-N
N-Methyl-L-alanyl-(2S)-2-cyclohexylglycyl-N-[(1R)-1,2,3,4-tetrahydro-1-naphthalenyl]-L-prolinamide hydrochloride
L-Prolinamide, N-methyl-L-alanyl-(2S)-2-cyclohexylglycyl-N-[(1R)-1,2,3,4-tetrahydro-1-naphthalenyl]-, monohydrochloride
L-ProlinaMide, N-Methyl-L-alanyl-(2S)-2-cyclohexylglycyl-N-[(1R)-1,2,3,4-tetrahydro-1-naphthalenyl]-, Monohydrochloride (9CI)
[Molecular Formula]

C27H41ClN4O3
[MOL File]

762274-58-8.mol
[Molecular Weight]

505.1
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

A 410099.1 is a BIRC inhibitor, with EC50 values for BIRC2, BIRC3, BIRC4, BIRC7, and BIRC8 are 4.6, 9.2, 15.6, 19.9, and 93.9 nM, respectively[1].
[storage]

Store at -20°C
[References]

[1] Schwalm MP, et al Toolbox for the Generation of Chemical Probes for Baculovirus IAP Repeat Containing Proteins. Front Cell Dev Biol. 2022 May 26;10:886537. DOI:10.3389/fcell.2022.886537
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