| Identification | Back Directory | [Name]
RU 26752 | [CAS]
76676-33-0 | [Synonyms]
7-propyl spirolactone
17α-Hydroxy-3-oxo-7α-propylpregn-4-ene-21-carboxylic acid γ-lactone
(7α,17α)-17-Hydroxy-3-oxo-7-propylpregn-4-ene-21-carboxylicacidγ-lactone
Pregn-4-ene-21-carboxylic acid, 17-hydroxy-3-oxo-7-propyl-, γ-lactone, (7α,17α)- | [Molecular Formula]
C25H36O3 | [MDL Number]
MFCD06201853 | [MOL File]
76676-33-0.mol | [Molecular Weight]
384.56 |
| Chemical Properties | Back Directory | [Boiling point ]
546.7±50.0 °C(Predicted) | [density ]
1.12±0.1 g/cm3(Predicted) | [storage temp. ]
−20°C | [solubility ]
DMSO: 20 mg/mL at 60 °C warming up for 20 minutes, soluble | [form ]
solid |
| Hazard Information | Back Directory | [Uses]
RU 26752 is a steroid hormone receptor antagonist. RU 26752 can prevent hypertension caused by aldosterone (HY-113313) in rats[1]. | [Biological Activity]
Mineralocorticoid receptor antagonist. Prevents aldosterone-induced hypertension in rats. | [References]
[1] M Kalimi, et al. Effects of antimineralocorticoid RU 26752 on steroid-induced hypertension in rats. Am J Physiol. 1990 May;258(5 Pt 1):E737-9. DOI:10.1152/ajpendo.1990.258.5.E737 |
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| Company Name: |
SIGMA-RBI
|
| Tel: |
800 736 3690 (Orders) |
| Website: |
www.sigma-aldrich.com |
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