| Identification | Back Directory | [Name]
1-(m-Trifluoromethylphenyl) piperazine (hydrochloride) | [CAS]
76835-14-8 | [Synonyms]
1-(m-Trifluoromethylphenyl) piperazine (hydrochloride)
Piperazine, 1-[3-(trifluoroMethyl)phenyl]-, dihydrochloride | [Molecular Formula]
C11H14ClF3N2 | [MOL File]
76835-14-8.mol | [Molecular Weight]
266.69 |
| Hazard Information | Back Directory | [Description]
1-(3-Trifluoromethylphenyl)piperazine (TFMPP) is an entactogenic drug which selectively promotes the release of serotonin. When used in combination with 1-benzylpiperazine, TFMPP increases both serotonin and dopamine, mirroring the effects of 3,4-methylenedioxymethamphetamine. Drug-drug synergism may induce seizures. TFMPP has been identified in party pills and powders. Its metabolism in rats has been described. This product is intended for forensic applications. | [References]
[1] MICHAEL H BAUMANN. N-Substituted Piperazines Abused by Humans Mimic the Molecular Mechanism of 3,4-Methylenedioxymethamphetamine (MDMA, or ‘Ecstasy’)[J]. Neuropsychopharmacology, 2004, 30 3: 550-560. DOI: 10.1038/sj.npp.1300585
[2] SIMON L HILL Simon H L T. Clinical toxicology of newer recreational drugs.[J]. Clinical Toxicology, 2011, 49 8: 705-719. DOI: 10.3109/15563650.2011.615318 |
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