| Identification | Back Directory | [Name]
4-AMino-2-chloro-1,3,5-triazine | [CAS]
7709-13-9 | [Synonyms]
4-chloro-1,3,5-triazin-2-amine
4-AMino-2-chloro-1,3,5-triazine
2-Amino-4-chloro-1,3,5-triazine
1,3,5-Triazin-2-amine, 4-chloro-
4-Chloro-[1,3,5]triazin-2-ylamine | [Molecular Formula]
C3H3ClN4 | [MDL Number]
MFCD19203794 | [MOL File]
7709-13-9.mol | [Molecular Weight]
130.54 |
| Chemical Properties | Back Directory | [Boiling point ]
383.3±25.0 °C(Predicted) | [density ]
1.566±0.06 g/cm3(Predicted) | [storage temp. ]
under inert gas (nitrogen or Argon) at 2–8 °C | [solubility ]
Dichloromethane, Methanol | [form ]
Solid | [pka]
2.62±0.10(Predicted) | [color ]
White |
| Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Uses]
A metabolite of atrazine (A794600). | [Synthesis]
General procedure for the synthesis of 4-chloro-1,3,5-triazin-2-amine from 2,4-dichloro-1,3,5-triazine: 2,4-dichloro-1,3,5-triazine (45 mg, 0.3 mmol) was added to 2 mL of aqueous NH4OH. The reaction mixture was stirred at -20 °C for 10 min, followed by filtration and washing with distilled water. The product was dried to afford 4-chloro-1,3,5-triazin-2-amine (18 mg, 46% yield) as a yellow solid, which could be used in subsequent reactions without further purification. Mass spectrometry (MS) analysis showed m/z: 131.0 ([M + H]+). | [References]
[1] Patent: WO2014/15523, 2014, A1. Location in patent: Page/Page column 126; 127
[2] Patent: WO2014/15830, 2014, A1. Location in patent: Page/Page column 151
[3] Agricultural and Biological Chemistry, 1982, vol. 46, # 6, p. 1439 - 1445
[4] Patent: WO2011/146882, 2011, A1. Location in patent: Page/Page column 108
[5] Patent: WO2014/15675, 2014, A1. Location in patent: Page/Page column 151; 152 |
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| Company Name: |
BePharm Ltd
|
| Tel: |
400-685-9117 |
| Website: |
www.bepharm.com |
|