Identification | Back Directory | [Name]
TROPONIN I | [CAS]
77108-40-8 | [Synonyms]
TNI HCTNL TROPONIN I TROPONIN I, HUMAN TROPONIN I (CARDIAC) TROPONIN I (SKELETAL) TROPONIN I, HUMAN HEART TROPONIN I-CARDIAC, HUMAN TROPONIN I, HUMAN CARDIAC TROPONIN I-SKELETAL, HUMAN TROPONIN I, HUMAN SKELETAL troponin I from human heart TroponinI from human heart,Tn-I TROPONIN I (HUMAN CARDIAC MUSCLE) TROPONIN I (HUMAN SKELETAL MUSCLE) Recombinant Human Cardiac Troponin-I Troponin I from human heart lyophilized powder | [Molecular Formula]
NULL | [MDL Number]
MFCD00213059 |
Hazard Information | Back Directory | [Uses]
Troponin I from human heart can be used in studies whether the actin and aldolase can protect rabbit muscle lactate dehydrogenase inhibition by ascorbate or not. | [General Description]
Native troponin I purified from human heart. Inhibitory subunit of troponin that binds to actin in the absence of Ca2+, thus inhibiting the ATPase activity of actomyosin. Presence of Tnl in plasma has been used for early detection of myocardial infarction. Useful as a standard in immunoassay and as an immunogen for anti-sera production. Also useful as a tracer for iodination. | [Biochem/physiol Actions]
Troponin I interacts with tropomyosin for regulating the contraction of striated muscle in a calcium-dependent manner. Additionally, Troponin I can also inhibits actomyosin ATPase and serves as a selective and potent inhibitor of angiogenesis in vivo and in vitro and of tumor metastasis in vivo. |
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