ChemicalBook--->CAS DataBase List--->77108-40-8

77108-40-8

77108-40-8 Structure

77108-40-8 Structure
IdentificationBack Directory
[Name]

TROPONIN I
[CAS]

77108-40-8
[Synonyms]

TNI
HCTNL
TROPONIN I
TROPONIN I, HUMAN
TROPONIN I (CARDIAC)
TROPONIN I (SKELETAL)
TROPONIN I, HUMAN HEART
TROPONIN I-CARDIAC, HUMAN
TROPONIN I, HUMAN CARDIAC
TROPONIN I-SKELETAL, HUMAN
TROPONIN I, HUMAN SKELETAL
troponin I from human heart
TroponinI from human heart,Tn-I
TROPONIN I (HUMAN CARDIAC MUSCLE)
TROPONIN I (HUMAN SKELETAL MUSCLE)
Recombinant Human Cardiac Troponin-I
Troponin I from human heart lyophilized powder
[Molecular Formula]

NULL
[MDL Number]

MFCD00213059
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[form ]

lyophilized powder
Safety DataBack Directory
[Hazard Codes ]

B
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

Troponin I from human heart can be used in studies whether the actin and aldolase can protect rabbit muscle lactate dehydrogenase inhibition by ascorbate or not.
[General Description]

Native troponin I purified from human heart. Inhibitory subunit of troponin that binds to actin in the absence of Ca2+, thus inhibiting the ATPase activity of actomyosin. Presence of Tnl in plasma has been used for early detection of myocardial infarction. Useful as a standard in immunoassay and as an immunogen for anti-sera production. Also useful as a tracer for iodination.
[Biochem/physiol Actions]

Troponin I interacts with tropomyosin for regulating the contraction of striated muscle in a calcium-dependent manner. Additionally, Troponin I can also inhibits actomyosin ATPase and serves as a selective and potent inhibitor of angiogenesis in vivo and in vitro and of tumor metastasis in vivo.
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