| Identification | Back Directory | [Name]
N6-ISOPENTENYLADENOSINE-D6 | [CAS]
7724-76-7 | [Synonyms]
2ipa
sq22558
riboprine
NSC-105546
Aids126321
Aids-126321
2-IP RIBOSIDE
N6-(Δ2-Isopent
Riboprine (IPA)
isopentenyladenosine
n-isopentenyladenosine
Dimethylallyladenosine
N6-(3-Methyl-2-butenyl)
N6-ISOPENTENYLADENOSINE
N6-ISOPENTENYLADENOSINE-D6
isopentenyladenineriboside
N6-[2-ISOPENTENYL]ADENOSINE
isopentenyladenosineriboside
n(sup6)-isopentenyladenosine
N6-ISOPENTENYLADENOSINE (iPR)
n(sup6)-dimethylallyladenosine
n-(3-methyl-2-butenyl)-adenosin
N-(3-Methyl-2-butenyl)adenosine
N6-(γ,γ-Dimethylallyl)adenosine
n(sup6)-(2-isopentenyl)adenosine
N6-(3-Methyl-2-butenyl)adenosine
N6-(DELTA2-ISOPENTENYL)-ADENOSINE
N6-(2-ISOPENTENYL)ADENINE RIBOSIDE
N6-(Δ2-isopentenyl)adenosine (IPA)
N6-ISOPENTENYLADENOSINE-D6 USP/EP/BP
N6-(2-ISOPENTENYL)ADENOSINE RIBOSIDE
Adenosine, N-(3-methyl-2-buten-1-yl)-
N6-(2-Isopentenyl) Adenosine pure, 98%
Adenosine, N-(3-methyl-2-butenyl)- ( )
N6-[GAMMA,GAMMA-DIMETHYLALLYL]ADENOSINE
n(sup6)-(delta(sup2)-isopentenyl)adenosine
6-(3,3-DIMETHYLALLYL-AMINO)PURINE RIBOSIDE
6-(3-Methyl-2-butenylamino)purine riboside
6-(GAMA,GAMA-DIMETHYLALLYLAMINO)PURINERIBOSIDE
2-iP riboside N6-(2-Isopentenyl)adenine riboside
N6-Isopentenyladenosine, Riboprine, 2iP riboside
6-(gamma,gamma-dimethylallylamino)*purine ribosid
6-(GAMMA,GAMMA-DIMETHYLALLYLAMINO)PURINE RIBOSIDE
6-(3-Methyl-2-butenylaMino)-9-β-ribofuranosylpurine
6-(3-Methyl-2-butenylaMino)-β,D-ribofuranosylpurine
6-(3-Methyl-2-butenylaMino)-9-β-D-ribofuranosylpurine
6-(3,3-Dimethylallylamino)-9-(β-D-ribofuranosyl)purine
6-(3,3-Dimethylallylamino)-9-(b-D-ribofuranosyl)purine
6-(3,3-Dimethylallylamino)-9-beta-D-ribofuranosylpurine
9.beta.-D-Ribofuranosyl-9H-purine, N-(3-methyl-2-butenylamino)-
N6-Iso pentenyl adenosine, Riboprine, antiviral antitumor agent
2iP Riboside, 6-(3,3-Dimethylallylamino)purine riboside, N6-(γ,γ-Dimethylallyl)adenosine, N6-(2-Isopentenyl)adenosine | [EINECS(EC#)]
231-771-3 | [Molecular Formula]
C15H21N5O4 | [MDL Number]
MFCD00005741 | [MOL File]
7724-76-7.mol | [Molecular Weight]
335.36 |
| Chemical Properties | Back Directory | [Melting point ]
142-143 °C(Solv: ethanol (64-17-5)) | [Boiling point ]
647.2±65.0 °C(Predicted) | [density ]
1.56±0.1 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [solubility ]
DMSO (Slightly), Methanol (Slightly, Heated, Sonicated) | [form ]
Solid | [pka]
13.12±0.70(Predicted) | [color ]
White to Light Beige |
| Hazard Information | Back Directory | [Description]
N6-(Δ2-Isopentenyl)adenosine is a precursor in the biosynthesis of the plant hormone N6-(Δ2-isopentenyl)adenine . N6-(Δ2-isopentenyl)adenine may be converted to the cytokinin trans-zeatin by cytochrome P450 mono-oxygenases. Cytokinins, including N6-(Δ2-isopentenyl)adenine and trans-zeatin, regulate diverse events in plant growth and development. N6-(Δ2-Isopentenyl)adenosine can also alter post-transcriptional processes in mammalian cells, altering proliferation and apoptosis. | [Chemical Properties]
White to off-white crystalline powder | [Uses]
[2H6] N6-Isopentenyladenosine-D6 can be used as analyte in analytical study for acetylation of cytokinins and modified adenine compounds for gas chromatography-mass spectrometric analysis. | [Uses]
N6-Isopentenyladenosine has antiproliferative activity on MCF-7 breast cancer cells. | [Definition]
ChEBI: A nucleoside analogue in which adenosine has been modified by substitution at the 6-amino nitrogen by a Delta2-isopentenyl group. | [References]
[1] NAOYA HIROSE. Regulation of cytokinin biosynthesis, compartmentalization and translocation.[J]. Journal of Experimental Botany, 2008: 75-83. DOI: 10.1093/jxb/erm157
[2] MAURIZIO BIFULCO. Biological and pharmacological roles of N6-isopentenyladenosine: an emerging anticancer drug.[J]. Anti-cancer agents in medicinal chemistry, 2008, 8 2: 200-204. DOI: 10.2174/187152008783497028
[3] SILVANA CASATI. Effects of cytokinins, cytokinin ribosides and their analogs on the viability of normal and neoplastic human cells.[J]. Anticancer research, 2011, 31 10: 3401-3406.
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