| Identification | Back Directory | [Name]
BETA-MERCAPTO-BETA,BETA-CYCLOPENTAMETHYLENE-PROPIONYL-TYR(ME)-ILE-GLN-ASN-CYS-PRO-ORN-GLY-NH2 | [CAS]
77327-45-8 | [Synonyms]
Mpomeovt
me)(2)-orn(8)-
[PMP1,TYR(OME)2,ORN8] VASOTOCIN
(D(CH2)(5/1),TYR(ME)2,ORN8)-OXYTOCIN
[D(CH2)51, TYR(ME)2, ORN8]-VASOTOCIN
(D(CH2)51,(METHYL)TYR2,ORN8)-OXYTOCIN
PMP-TYR(ME)-ILE-GLN-ASN-CYS-PRO-ORN-GLY-NH2
(d(CH?)??,Tyr(Me)?,Orn?)-Oxytocin trifluoroacetate salt
[β-mercapto-β,β-cyclopentamethylenepropionyl1, o-me-tyr2, orn8]-oxytocin
oxytocin,1-(beta-mercapto-(beta,beta-cyclopentamethylene)propionicacid)-tyr(o
b-Mercapto-b,b-cyclopentaMethylene-propionyl-Tyr(Me)-Ile-Gln-Asn-Cys-Pro-Orn-Gly-NH2
BETA-MERCAPTO-BETA,BETA-CYCLOPENTAMETHYLENE-PROPIONYL-TYR(ME)-ILE-GLN-ASN-CYS-PRO-ORN-GLY-NH2
1-(β-Mercapto-β,β-cyclopentamethylenepropionic acid)-2-O-methyltyrosine-8-ornithine]vasotocin
oxytocin,1-(beta-mercapto-(beta, beta-cyclopentamethylene)propionic acid)-Tyr(OMe)(2)-Orn(8)-
beta-Mercapto-beta,beta-cyclopentamethylenepropionyl1, O-Me-Tyr2, Orn8]-Oxytocin >=93% (HPLC), solid
beta-Mercapto-beta,beta-cyclopentamethylene-propionyl-Tyr(Me)-Ile-Gln-Asn-Cys-Pro-Orn-Gly-NH2, (Disulfide bond)
Glycinamide, N-[(1-mercaptocyclohexyl)acetyl]-O-methyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-ornithyl-, cyclic (1→5)-disulfide (9CI) | [Molecular Formula]
C48H74N12O12S2 | [MDL Number]
MFCD00135712 | [MOL File]
77327-45-8.mol | [Molecular Weight]
1075.3 |
| Chemical Properties | Back Directory | [Boiling point ]
1537.6±65.0 °C(Predicted) | [density ]
1.36±0.1 g/cm3(Predicted) | [storage temp. ]
−20°C | [form ]
solid | [pka]
12.85±0.70(Predicted) | [Sequence]
{β-Mercapto-β,β-cyclopentamethylene-propionyl-Tyr(Me)}-Ile-Gln-Asn-Cys-Pro-{Orn}-Gly-NH2 (disulfide bridge: mercaptopropanoic acid-1-cysteine-6) | [InChIKey]
ZWVZXPFUQHTUKV-SZQHDTAUSA-N |
| Hazard Information | Back Directory | [Uses]
[β-Mercapto-β,β-cyclopentamethylenepropionyl1, O-Me-Tyr2, Orn8]-Oxytocin has been used as an oxytocin receptor antagonist:
- to study the influence of blockading the oxytocin receptors in the anterior cingulate cortex on helping behavior
- to determine the receptors that mediate vasopressin-stimulated anion secretion across cultured porcine vas deferens epithelial cell monolayers
- to study the influence of oxytocin receptors inhibition on intravenous and in situ oxytocin effects on the urinary bladder and cardiovascular activities in sham rats
| [Biochem/physiol Actions]
[β-Mercapto-β,β-cyclopentamethylenepropionyl1, O-Me-Tyr2, Orn8]-also acts as an arginine vasopressin receptor 1A (AVPR1A) antagonist. |
|
| Company Name: |
BOC Sciences
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1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
Sigma-Aldrich
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021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Energy Chemical
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021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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