| Identification | Back Directory | [Name]
Retosiban | [CAS]
820957-38-8 | [Synonyms]
Retosiban
GSK 221149
GSK 221149A
Retosiban (GSK 221149
GSK221149A (Retosiban)
GSK-221149A; GSK 221149A
2,5-Piperazinedione, 3-(2,3-dihydro-1H-inden-2-yl)-1-[(1R)-1-(2-methyl-4-oxazolyl)-2-(4-morpholinyl)-2-oxoethyl]-6-[(1S)-1-methylpropyl]-, (3R,6R)- | [Molecular Formula]
C27H34N4O5 | [MDL Number]
MFCD19443707 | [MOL File]
820957-38-8.mol | [Molecular Weight]
494.58 |
| Chemical Properties | Back Directory | [Boiling point ]
770.0±60.0 °C(Predicted) | [density ]
1.257±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
13.07±0.60(Predicted) | [color ]
Off-white to yellow |
| Hazard Information | Back Directory | [Uses]
Retosiban (GSK221149A) is a potent and selective oxytocin antagonist with a Ki of 0.65 nM. | [Definition]
ChEBI: Retosiban is a dipeptide. | [storage]
Store at -20°C | [References]
[1] Liddle J, et al. The discovery of GSK221149A: a potent and selective oxytocin antagonist. Bioorg Med Chem Lett. 2008 Jan 1;18(1):90-4. DOI:10.1016/j.bmcl.2007.11.008 |
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| Company Name: |
BOC Sciences
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| Tel: |
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| Website: |
https://www.bocsci.com |
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