ChemicalBook--->CAS DataBase List--->7755-01-3

7755-01-3

7755-01-3 Structure

7755-01-3 Structure
IdentificationBack Directory
[Name]

Protopanaxadiol
[CAS]

7755-01-3
[Synonyms]

Protopanaxadiol
20R-Protopanaxadiol
(20R)-Protopanaxadiol
20R-Betulafolienetriol
Protopanaxadiol USP/EP/BP
PROTOVERATRINE A+B (RG)(CALL)
(20R)-Dammar-24-ene-3β,12β,20-triol
(20R)-5α-Dammar-24-ene-3β,12β,20-triol
Dammar-24-ene-3,12,20-triol, (3β,12β,20R)-
Protopanaxadiol, 98%, from Panax ginseng C. A. Mey.
[Molecular Formula]

C30H52O3
[MDL Number]

MFCD01861516
[MOL File]

7755-01-3.mol
[Molecular Weight]

460.732
Chemical PropertiesBack Directory
[Boiling point ]

559.5±40.0 °C(Predicted)
[density ]

1.036±0.06 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
[form ]

powder
[pka]

14.96±0.70(Predicted)
[color ]

White
Hazard InformationBack Directory
[Description]

(20)R-Protopanaxadiol is a sapogenin that has been found in P. ginseng and has anticancer and antibacterial activities. It has a cytotoxic concentration (CC50) value of 6.1 μM in MT-4 human T cell leukemia cells and inhibits the growth of several additional cancer cell lines, including A549 human lung carcinoma, SKOV3 human ovarian adenocarcinoma, SK-Mel-2 human melanoma, P388 and L1210 murine leukemia, and K562 human chronic leukemia cells (ED50s = 11-26 μM). (20)R-protopanaxadiol also inhibits the growth of H. pylori in vitro (MICs = 50-100 μg/ml).
[Uses]

20(R)-Protopanaxdiol is a saponin ginsenoside which is a signature phytochemical of Ginseng, an herbaceous plant. Anti-cancer agent.
[Definition]

ChEBI: A diastereomer of protopanaxadiol in which the 20-hydroxy substituent has been introduced at the pro-R position.
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