| Identification | Back Directory | [Name]
BL 6341A | [CAS]
78441-84-6 | [Synonyms]
BL 6341A
Guanidine, [4-[[[2-[(4-amino-1-oxido-1,2,5-thiadiazol-3-yl)amino]ethyl]thio]methyl]-2-thiazolyl]- (9CI) | [Molecular Formula]
C9H14N8OS3 | [MOL File]
78441-84-6.mol | [Molecular Weight]
346.455 |
| Chemical Properties | Back Directory | [Boiling point ]
609.7±65.0 °C(Predicted) | [density ]
1.4855 (rough estimate) | [refractive index ]
1.7400 (estimate) | [pka]
8.52±0.70(Predicted) |
| Hazard Information | Back Directory | [Uses]
BL 6341A is an antagonist for histamine H2 receptor with Ki of 3.5-4.4 nM, that inhibits histamine-induced acid secretion and cAMP formation. BL 6341A can be used in research of gastric acid secretion related diseases, such as gastric ulcer or gastroesophageal reflux[1]. | [References]
[1] Batzri S, et al., Distortion of H2-antagonist equilibrium constants by uptake in rabbit gastric mucosal cells. Pharmacology. 1985;30(4):215-24. DOI:10.1159/000138071 |
|
|