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787583-71-5

787583-71-5 Structure

787583-71-5 Structure
IdentificationBack Directory
[Name]

[1,1'-Biphenyl]-4-carboxylic acid, 2'-[(1R)-1-[(2R)-3-[[2-(4-chloro-3-fluorophenyl)-1,1-diMethylethyl]aMino]-2-hydroxypropoxy]ethyl]-3-Methyl-
[CAS]

787583-71-5
[Synonyms]

JIT305
JIT 305
Encaleret
UNFHDRVFEQPUEL-DENIHFKCSA-N
1,1'-Biphenyl]-4-carboxylic acid, 2'-[(1R)-1-[(2R)-3-[[2-(4-chloro-3-fluorophenyl)-1,1-diMethylethyl]aMino]-2-hydroxypropoxy]ethyl]-3-Methyl-
[1,1'-Biphenyl]-4-carboxylic acid, 2'-[(1R)-1-[(2R)-3-[[2-(4-chloro-3-fluorophenyl)-1,1-diMethylethyl]aMino]-2-hydroxypropoxy]ethyl]-3-Methyl-
[Molecular Formula]

C29H33ClFNO4
[MDL Number]

MFCD18781879
[MOL File]

787583-71-5.mol
[Molecular Weight]

514.03
Chemical PropertiesBack Directory
[Boiling point ]

673.5±55.0 °C(Predicted)
[density ]

1.216±0.06 g/cm3(Predicted)
[form ]

Solid
[pka]

3.88±0.25(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

Encaleret (CLTX-305) is an orally active CaSR antagonist[1].
[References]

[1] Discovery of a Potent and Short Acting Oral Calcilytic with a Pulsatile Secretion of Parathyroid Hormone Publication Date (Web): December 29, 2010 (Letter)
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