| Identification | Back Directory | [Name]
11BETA-HYDROXYPROGESTERONE | [CAS]
600-57-7 | [Synonyms]
21-deoxycorticosterone
11B-HYDROXYPROGESTERONE
11β-hydroxyprogesterone
HYDROXYPROGESTERONE, 11B-
11BETA-HYDROXYPROGESTERONE
4-PREGNEN-11BETA-3,20-DIONE
4-PREGNEN-11BETA-OL-3,20-DIONE
11beta-Hydroxyprogesterone, >98%
Progesterone 11beta-Hydroxy Impurity
11-beta-hydroxy-pregn-4-ene-20-dione
11-beta-hydroxypregn-4-ene-3,20-dione
11-BETA-HYDROXY-4-PREGNENE-3,20-DIONE
11-hydroxy-20-dion(11-beta)-pregn-4-ene-
Pregn-4-ene-3,20-dione,11-hydroxy-, (11b)-
Pregn-4-ene-3,20-dione, 11-hydroxy-, (11β)-
17-acetyl-11-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one | [EINECS(EC#)]
209-995-8 | [Molecular Formula]
C21H30O3 | [MDL Number]
MFCD00064137 | [MOL File]
600-57-7.mol | [Molecular Weight]
330.46 |
| Chemical Properties | Back Directory | [Melting point ]
181～184℃ | [Boiling point ]
487.4±45.0 °C(Predicted) | [density ]
1.15±0.1 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
Acetone (Slightly), Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
14.52±0.70(Predicted) | [color ]
White to Off-White | [Water Solubility ]
30.84mg/L(37 ºC) |
| Hazard Information | Back Directory | [Uses]
11β-Hydroxy Progesterone is a derivative of Progesterone (P755900) is a steroid hormone produced by the corpus luteum. Induces maturation and secretory activity of the uterine endothelium; suppresses ovulation. Progesterone is implicated in the etiology of breast cancer.This compound is a contaminant of emerging concern (CECs). | [Definition]
ChEBI: 11beta-hydroxyprogesterone is a 11beta-hydroxy steroid that is progesterone substituted by a beta-hydroxy group at position 11. It has a role as a human metabolite and a mouse metabolite. It is functionally related to a progesterone. | [in vivo]
11β-hydroxyprogesterone causes a significant elevation in blood pressure within 3 days, an effect that persisted throughout the 14-day infusion. 11β-hydroxyprogesterone is potently hypertensinogenic in the rat and that this activity depends on an intact adrenal and at least in part on the activation of mineralocorticoid receptors[2]. | [IC 50]
Human Endogenous Metabolite | [storage]
Store at -20°C |
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