| Identification | Back Directory | [Name]
A-3 HYDROCHLORIDE | [CAS]
78957-85-4 | [Synonyms]
A-3
A-3 HYDROCHLORIDE
TRISIALYLATED, GALACTOSYLATED, TRIANTENNARY
N-(2-AMINOETHYL)-5-CHLORONAPHTHALENE-1-SULFONAMIDE HCL
N-(2-AMINOETHYL)-5-CHLORONAPHTHALENE-1-SULFONAMIDE HYDROCHLORIDE
N-(2-AMINOETHYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE HYDROCHLORIDE
N-(2-AMINOETHYL)-5-CHLORONAPHTHALENE-1-SULPHONAMIDE HYDROCHLORIDE | [Molecular Formula]
C12H14Cl2N2O2S | [MDL Number]
MFCD00077311 | [MOL File]
78957-85-4.mol | [Molecular Weight]
321.22 |
| Chemical Properties | Back Directory | [Appearance]
White Crystalline Solid | [Melting point ]
173-176°C | [storage temp. ]
−20°C
| [solubility ]
DMSO: 24 mg/mL
| [form ]
solid
| [color ]
white
| [InChI]
1S/C12H13ClN2O2S.ClH/c13-11-5-1-4-10-9(11)3-2-6-12(10)18(16,17)15-8-7-14;/h1-6,15H,7-8,14H2;1H | [InChIKey]
VWAGIWCLJAQLAL-UHFFFAOYSA-N | [SMILES]
Cl[H].NCCNS(=O)(=O)c1cccc2c(Cl)cccc12 |
| Hazard Information | Back Directory | [Chemical Properties]
White Crystalline Solid | [Uses]
Inhibits cAMP and cGMP dependent protein kinases. Also inhibits MLC kinase and protein kinase C | [Biochem/physiol Actions]
Non-selective casein kinase (CK) inhibitor. A shorter alkyl chain derivative of W-7 that inhibits casein kinase I (Ki = 80 μM), casein kinase II (Ki = 5.1 μM), myosin light chain kinase (Ki = 7.4 μM), protein kinase A (Ki = 4.3 μM), protein kinase C (Ki= 47 μM), and protein kinase G (Ki = 3.8 μM). | [IC 50]
CK1: 80 μM (Ki); CK2: 5.1 μM (Ki); PKC: 47 μM (Ki); PKA: 4.3 μM (Ki) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
36/37/38 | [Safety Statements ]
26-36 | [WGK Germany ]
3
| [HS Code ]
2935909099 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Sigma-Aldrich
|
| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|