| Identification | More | [Name]
2,6-Dichlorophenylhydrazine hydrochloride | [CAS]
50709-36-9 | [Synonyms]
1-(2,6-DICHLOROPHENYL)HYDRAZINE HYDROCHLORIDE
2,6-DICHLOROPHENYLHYDRAZINE HCL
2,6-DICHLOROPHENYLHYDRAZINE HYDROCHLORIDE
2,6-Dichoropheynylhydrazine hydrochloride
(2,6-dichlorophenyl)hydrazine monohydrochloride
2,6-Dichlorophenylhydrazine hydrochloride, 98+%
Hydrazine, (2,6-dichlorophenyl)-, monohydrochloride | [EINECS(EC#)]
256-730-7 | [Molecular Formula]
C6H7Cl3N2 | [MDL Number]
MFCD00012930 | [Molecular Weight]
213.49 | [MOL File]
50709-36-9.mol |
| Chemical Properties | Back Directory | [Appearance]
white to light yellow powder | [Melting point ]
225 °C (dec.)(lit.) | [Boiling point ]
346.49°C (rough estimate) | [density ]
1.6100 (rough estimate) | [refractive index ]
1.6000 (estimate) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [form ]
powder to crystal | [color ]
White to Light yellow to Light orange | [BRN ]
4569738 | [CAS DataBase Reference]
50709-36-9(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
T,Xi,Xn | [Risk Statements ]
R20/21:Harmful by inhalation and in contact with skin .
R25:Toxic if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S22:Do not breathe dust . | [RIDADR ]
UN 2811 6.1/PG 3
| [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HazardClass ]
6.1 | [PackingGroup ]
Ⅲ | [HS Code ]
29280000 |
| Hazard Information | Back Directory | [Chemical Properties]
white to light yellow powder | [Uses]
(2,6-Dichlorophenyl)hydrazine Hydrochloride | [Uses]
2,6-Dichlorophenylhydrazine hydrochloride was used in the preparation of 1-(2,6-dichlorophenyl)-4-methyl-5-(4-methoxyphenyl)-1H-pyrazole-3-carboxylic acid, ethyl ester. | [Synthesis]
General procedure for the synthesis of 2,6-dichlorophenylhydrazine hydrochloride from 2,6-dichloroaniline: 2,6-dichloroaniline (10.0 g, 61.72 mmol) was dissolved in an appropriate amount of solvent and cooled to -15 °C. At this temperature, aqueous sodium nitrite (5.11 g, 74.00 mmol) and hydrochloric acid were slowly added. The reaction mixture was stirred at 0-10°C for 15 minutes. The reaction mixture was filtered to remove insoluble matter and subsequently concentrated hydrochloric acid (34.7 g, 150 mmol) was added to the filtrate. The reaction system was maintained at -15 °C and stirring was continued for 30 min, after which the precipitate was collected by filtration to afford 15.00 g of the target product 2,6-dichlorophenylhydrazine hydrochloride. The product was characterized by 1H NMR (300 MHz, DMSO-d6): δ 7.18-7.28 (m, 1H), 7.39-7.52 (m, 2H), 10.30 (br s, 3H); the mass spectrum (MS) showed m/z: 176.90 (M)+. | [References]
[1] Patent: WO2013/186692, 2013, A1. Location in patent: Page/Page column 103; 104 |
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