| Identification | Back Directory | [Name]
Diammonium glycyrrhizinate | [CAS]
79165-06-3 | [Synonyms]
DiaMMoniuM Glycyrrhizate
Diammonium Glycyrrhizinat
Diammonium glycyrrhizinate
a-D-Glucopyranosiduronic acid
18A-DIAMMONIUM GLYCYRRHIZINATE
18α-DIAMMONIUM GLYCYRRHIZINATE
GLYCYRRHIZICACIDDIAMMONIUMSALT | [EINECS(EC#)]
1308068-626-2 | [Molecular Formula]
C42H62O16.2H3N | [MDL Number]
MFCD09038726 | [MOL File]
79165-06-3.mol | [Molecular Weight]
856.997 |
| Chemical Properties | Back Directory | [storage temp. ]
Inert atmosphere,2-8°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [color ]
White to off-white | [InChIKey]
ILRKKHJEINIICQ-OOAQPTSPNA-N |
| Hazard Information | Back Directory | [Description]
Diammonium Glycyrrhizinate is the diammonium salt of glycyrrhizin and the active constituent in the traditional Chinese medicinal herb Glycyrrhiza uralensis (Chinese liquorice or Gan-Cao) with anti-inflammatory, antioxidant and hepatoprotective properties. Diammonium glycyrrhizinate (DG) is slowly metabolized within the cells into glycyrrhetic acid, which inhibits enzymes that control cortisol metabolism and contributes to this agent's anti-inflammatory effect. Although the exact mechanism of action remains to be fully elucidated, DG may prevent or reduce hepatotoxicity via the scavenging of free radicals. This agent also upregulates the expression of transcription coactivator PGC-1alpha and modulates hepatic enzymes such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), superoxide dismutase and glutathion peroxidase. | [Occurrence]
Diammonium glycyrrhizinate, a traditional Chinese medicine (TCM), is extracted and purified from liquorices (Radix glycyrrhizae). | [Uses]
Diammonium Glycyrrhizinate is effective against Porcine parvovirus (PPV) in vitro. | [storage]
Store at 4°C, protect from light, filled inert atmosphere |
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