ChemicalBook--->CAS DataBase List--->79598-53-1

79598-53-1

79598-53-1 Structure

79598-53-1 Structure
IdentificationBack Directory
[Name]

6-Azido-hexanoic acid
[CAS]

79598-53-1
[Synonyms]

e-Azidocaproic acid
6-Azido-hexanoic acid
6-Azidohexanoic acid >=95%
6-Azidohexanoic acid - A1945
[Molecular Formula]

C6H11N3O2
[MDL Number]

MFCD12406156
[MOL File]

79598-53-1.mol
[Molecular Weight]

157
Chemical PropertiesBack Directory
[density ]

1.074 g/mL
[refractive index ]

n/D 1.463
[storage temp. ]

2-8°C
[solubility ]

Chloroform (Slightly), Methanol (Slightly)
[form ]

Oil
[color ]

Colourless to Pale Yellow
[Stability:]

Light Sensitive
[InChI]

InChI=1S/C6H11N3O2/c7-9-8-5-3-1-2-4-6(10)11/h1-5H2,(H,10,11)
[InChIKey]

JCORXJUUSVCJEP-UHFFFAOYSA-N
[SMILES]

C(O)(=O)CCCCCN=[N+]=[N-]
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P261-P264-P271-P280-P302+P352-P305+P351+P338
[Safety Statements ]

24/25
[HS Code ]

29270000
Hazard InformationBack Directory
[Description]

6-Azido-hexanoic acid is a linker containing an azide group and a terminal carboxylic acid. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
[Chemical Properties]

Colorless to yellow oil
[Uses]

6-Azidohexanoic acid is a six-carbon saturated fatty acid with an ω-terminal azide group. This building block can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC), forming a stable amide bond. The terminal azide group allows conjugation with compounds containing alkyne groups through a copper(I)-catalyzed cycloaddition reaction, also known as click chemistry. 6-Azidohexanoic acid is useful for crosslinking, synthesis of chemical probes, and other bioconjugation strategies.
[reaction suitability]

reagent type: cross-linking reagent
Spectrum DetailBack Directory
[Spectrum Detail]

6-Azido-hexanoic acid(79598-53-1)1HNMR
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