ChemicalBook--->CAS DataBase List--->8016-63-5

8016-63-5

8016-63-5 Structure

8016-63-5 Structure
IdentificationBack Directory
[Name]

Clary sage oil
[CAS]

8016-63-5
[Synonyms]

FEMA 2321
CLARYSAGE
Clary oil
CLARYEXTRACT
CLARY SAGE OIL
SAGE OIL CLARY
CLARY SAGE OIL FCC
SAGECLARYOIL,RUSSIAN
Sage oil, muscatel
OLEUMSALVIAESCLARIAE
Clary sage oil ester
SALVIA SCLAREA (CLARY) OIL
Muscatel sage oil Salvia sclarea L.
Clarysageoil=Muscatelsageoilexsalviasclarea
MUSCATEL SAGEOIL FROM SALVIA SCLAREA L., NATURAL
[MDL Number]

MFCD00287083
Chemical PropertiesBack Directory
[Boiling point ]

210 °C(lit.)
[density ]

0.89 g/mL at 25 °C(lit.)
[FEMA ]

2321
[refractive index ]

n20/D 1.458(lit.)
[Fp ]

187 °F
[storage temp. ]

2-8°C
[Odor]

at 100.00 %. herbal floral green spicy hay lavender tea soapy pimenta dill
[Odor Type]

herbal
[Cosmetics Ingredients Functions]

TONIC
SKIN CONDITIONING - EMOLLIENT
FRAGRANCE
[Uses]

clary sage oil (Salvia sclarea) could be beneficial in products designed for use around the eyes because of its soothing and antiinflammatory properties. It is used to refresh the skin and can also mask odors. In addition, its fragrance may have aroma therapeutic value, such as promoting cell regeneration for normal, dry, and sensitive skin types.
[EPA Substance Registry System]

Oils, clary sage(8016-63-5)
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

38
[WGK Germany ]

2
[RTECS ]

GF1170000
[TSCA ]

TSCA listed
[Toxicity]

LD50 orl-rat: 5600 mg/kg FCTXAV 12,865,74
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Salvia Root P.E Tanshinone IIA 20%-->SAGE OIL, SPANISH
Hazard InformationBack Directory
[Chemical Properties]

Clary sage oil is obtained by steam distillation of flowering tops and foliage of Salvia sclarea L. (Lamiaceae). It is a pale yellow to yellow liquid with a fresh herbaceous odor and a wine-like bouquet.
d2020 0.890–0.908; n20D 1.4560-1.4660; α20D ?10 ° to ?26 °; ester value: 180–235 corresponding to an ester content of 63–82% calculated as linalyl acetate; solubility: 1 vol in max. 3 vol 80% ethanol; content by GC: 56–78% linalyl acetate and 6.5–24% linalool.
In addition to linalyl acetate, the oil contains linalool and other terpene alcohols, as well as their acetates. When the volatile components are evaporated, a distinct ambergris note develops, which is attributed to oxidative degradation products of sclareol.
Clary sage is mainly grown in Eastern Europe (Ukraine,Moldova), France, the United States, and China. By far, the main part of the crop is used to prepare clary sage extract (concrete) by solvent extraction.Theconcrete is almost exclusively used to isolate its main constituent, the diterpene sclareol.
[Chemical Properties]

The essential oil, sometimes called muscatel, is obtained by steam or water distillation of flowering tops and leaves with yields ranging between 0.7 to 1.5%. It is produced in large quantities in France, Russia and Morocco. The Italian production is fairly small.
[Physical properties]

The essential oil of French production is a yellow liquid. The physical–chemical characteristics vary, depending on the source; minor components also vary. The oil is soluble in most fixed oils, and in mineral oil up to three volumes, but becomes opalescent on further dilution. It is insoluble in glycerin and in propylene glycol.
[Occurrence]

Found in the leaves and flowering tops of Salvia sclarea L. (Fam. Labiatae) (Gildemeister & Hoffman, 1961 ; Naves, 1974).
[Definition]

Extractives and their physically modified derivatives. Salvia sclarea, Labiatae.
[Preparation]

By steam distillation of the flowering tops and leaves of Salvia sclarea L. (Naves, 1974).
[Essential oil composition]

The main constituents of clary sage oil are linalyl acetate and linalool
[Safety Profile]

Low toxicity by ingestion. A skinirritant. When heated to decomposition it emits acridsmoke and irritating vapors.
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