| Identification | More | [Name]
3,4,5-TRIFLUOROBENZOTRIFLUORIDE | [CAS]
80172-04-9 | [Synonyms]
1,2,3-TRIFLUORO-5-TRIFLUOROMETHYL-BENZENE
3,4,5-TRICHLORO-TRIFLUOROTOLUENE
3,4,5-TRIFLUOROBENZOTRIFLUORIDE
ALPHA,ALPHA,ALPHA,3,4,5-HEXAFLUOROTOLUENE
3,4,5-Trifluorobenzotrifluoride, 97+%
2,4,5-Trifluorobenzotrifluorid | [Molecular Formula]
C7H2F6 | [MDL Number]
MFCD00153280 | [Molecular Weight]
200.08 | [MOL File]
80172-04-9.mol |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H315-H319-H335 | [Precautionary statements ]
P261-P271-P280 | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
2903998090 |
| Hazard Information | Back Directory | [Synthesis]
The general procedure for the synthesis of 3,4,5-trichlorobenzotrifluoride from 3,4,5-trichlorobenzotrifluoride was as follows: 860 g of dried cyclobutanesulfone and 524 g of dried potassium fluoride (KF) were added to an autoclave followed by the addition of an appropriate amount of water. Next, 500 g of 3,4,5-trichlorobenzotrifluoride, 5 g of nitrobenzene and 25 g of CNC catalyst were added. After sealing the autoclave, the reaction mixture was heated to 200 °C and maintained for 5 hours, then warmed up to 220 °C to continue the reaction for 12 hours. The maximum total pressure was controlled at 9 bar during the reaction. Upon completion of the reaction, the mixture was cooled to 20 °C and the product was transferred to the cooled receiver by depressurization. Subsequently, the product was distilled at standard pressure. The crude product was redistilled to give 300 g of 3,4,5-trifluorobenzotrifluoride in 75% of the theoretical value and the product was a colorless liquid. | [References]
[1] Patent: US2006/9643, 2006, A1. Location in patent: Page/Page column 5 |
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