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80295-38-1

80295-38-1 Structure

80295-38-1 Structure
IdentificationBack Directory
[Name]

C1 ESTERASE INHIBITOR
[CAS]

80295-38-1
[Synonyms]

C1 ESTERASE INHIBITOR
V:C1esteraseinhibitor
ESTERASE INHIBITOR C-1
C1-ESTERASE INHIBITOR, HUMAN
complement c1 esterase inhibitor
C1 INIHIBITOR (ESTERASE INIHIBITOR)
C1 ESTERASE INHIBITOR, HUMAN ANTIGEN
COMPLEMENT C1-ESTERASE INHIBITOR, HUMAN
c1 esterase inhibitor from human plasma
esterase inhibitor C-1 from*human plasma
Complement C1 esterase inhibitor, Esterase inhibitor C-1 from human plasma
[MDL Number]

MFCD00212908
Chemical PropertiesBack Directory
[storage temp. ]

-70°C
[form ]

aqueous solution
[biological source]

human plasma
Safety DataBack Directory
[Hazard Codes ]

B
[WGK Germany ]

3
Hazard InformationBack Directory
[General Description]

C1 esterase inhibitor is a single chain glycoprotein which inhibits C1, C1r, C1s, plasma kallikrein, factors XIa, XIIa and plasmin of the blood clotting system. It is present in the plasma at 16-33 mg/100mL. It is part of the serpin family.
[Biochem/physiol Actions]

Esterase inhibitor C1 is a multifunctional regulator of all major kinin-generating protein cascade systems. It has been a therapeutic tool in the treatment of hereditary angioedema and complement-mediated inflammatory tissue damage such as capillary leak syndrome, septic shock, multiple organ failure, and hyperacute graft rejection.
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