| Identification | Back Directory | [Name]
C8, HUMAN | [CAS]
80295-58-5 | [Synonyms]
C8, HUMAN
COMPLEMENT C8
COMPLEMENT C8, HUMAN
complement c8 from human serum
COMPLEMENT C8 FROM HUMAN SERUMFROZEN SOL UTION | [MDL Number]
MFCD00130847 |
| Hazard Information | Back Directory | [Uses]
Native, human C8 complement component. Glycoprotein composed of three non-identical subunits of M.W. 64 kDa (α), 64 kDa (β), and 22 kDa (γ). Present in normal human serum at 55 µg/ml. On activation of complement via either the classical or alternative pathway, C5 is cleaved into C5a and C5b fragments. The nascent C5b fragment binds to C6, C7, and C8 resulting in formation of the C5b-8 complex on target surfaces. Each membrane-bound, hydrophobic C5b-8 complex combines with three to six C9 molecules to complete the assembly of the lytic C5b-9 complement membrane attack complex (MAC). |
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| Company Name: |
Merck Millipore
|
| Tel: |
1-400-889-1988 400-889-1988 |
| Website: |
http://www.merckmillipore.com |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
| Company Name: |
SIGMA-RBI
|
| Tel: |
800 736 3690 (Orders) |
| Website: |
www.sigma-aldrich.com |
| Company Name: |
kemikalieimport
|
| Tel: |
+ 45 - 2034 3359 |
| Website: |
www.kemikalieimport.dk |
|