| Identification | Back Directory | [Name]
CECROPIN B | [CAS]
80451-05-4 | [Synonyms]
CECROPIN B
Aids096161
Aids-096161
Cecropin B, ≥97% (HPLC)
KWKVFKKIEKMGRNIRNGIVKAGPAIAVLGEAKAL-NH2
Cecropin B (Platysamiacecropia antibacterial peptide) (9CI)
LYS-TRP-LYS-VAL-PHE-LYS-LYS-ILE-GLU-LYS-MET-GLY-ARG-ASN-ILE-ARG-ASN-GLY-ILE-VAL-LYS-ALA-GLY-PRO-ALA-ILE-ALA-VAL-LEU-GLY-GLU-ALA-LYS-ALA-LEU-NH2
H-LYS-TRP-LYS-VAL-PHE-LYS-LYS-ILE-GLU-LYS-MET-GLY-ARG-ASN-ILE-ARG-ASN-GLY-ILE-VAL-LYS-ALA-GLY-PRO-ALA-ILE-ALA-VAL-LEU-GLY-GLU-ALA-LYS-ALA-LEU-NH2
Cecropin B H-Lys-Trp-Lys-Val-Phe-Lys-Lys-Ile-Glu-Lys-Met-Gly-Arg-Asn-Ile-Arg-Asn-Gly-Ile-Val-Lys-Ala-Gly-Pro-Ala-Ile-Ala-Val-Leu-Gly-Glu-Ala-Lys-Ala-Leu-NH2 | [Molecular Formula]
C176H302N52O41S | [MDL Number]
MFCD00130753 | [MOL File]
80451-05-4.mol | [Molecular Weight]
3834.67 |
| Chemical Properties | Back Directory | [storage temp. ]
−20°C
| [form ]
powder
| [color ]
White to off-white | [Water Solubility ]
Water : 20 mg/mL (5.22 mM) | [Sequence]
H-Lys-Trp-Lys-Val-Phe-Lys-Lys-Ile-Glu-Lys-Met-Gly-Arg-Asn-Ile-Arg-Asn-Gly-Ile-Val-Lys-Ala-Gly-Pro-Ala-Ile-Ala-Val-Leu-Gly-Glu-Ala-Lys-Ala-Leu-NH2 | [InChIKey]
YIQHNFUJWYYSEC-MQAAYMCRSA-N |
| Hazard Information | Back Directory | [Uses]
Cecropin B is an antibacterial peptide isolated from pig intestine and moths. | [Biological Activity]
Antibacterial peptide originally identified in moths (Hyalophora cecropia) and later in pig intestine.''Cecropin B is known for its antimicrobial activity. It displays antitumor effects in hepatocellular carcinomalymphomaand leukemia cell lines. | [in vivo]
The wounds are moist with more exudation in C group, while that in other groups are dry without obvious exudation. The body temperature of the majority of the mice in each group is elevated, but the number of leucocytes in each group is lowered after operation. The quantity of bacteria in muscle in A group is obviously lower than that in M group and C group. The number of surviving mice after 4 PID in C group is evidently smaller than that in A and M groups( P<0. 05)[2]. | [IC 50]
CYP3 |
|
|