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80506-64-5

80506-64-5 Structure

80506-64-5 Structure
IdentificationBack Directory
[Name]

AMINOPOLYETHYLENE GLYCOL 5'000 MONOMETHYL ETHER
[CAS]

80506-64-5
[Synonyms]

PEG NH2
mPEG-NH2
methoxyPEG amine
AMINOPOLYETHYLENE
MPEG-NH2 (Mn= 2,000)
AMINOPOLYETHYLENE GLYCOL 5
MPEGn-NH2 2K, 5K, 10K, 20K
Methoxypolyoxyethylene amine
MPEG-AMine, average M.W. 4,000
MPEG-AMine, average M.W. 1,000
MPEG-AMine, average M.W. 5,000
MPEG-AMine, average M.W. 6,000
MPEG-AMine, average M.W. 2,000
MPEG-AMine, average M.W. 20,000
MPEG-AMine, average M.W. 30,000
MPEG-AMine, average M.W. 10,000
mPEG-NH2, 95%, average M.W. 4,000
α-Amino-ω-methoxy polyoxyethylene
Methoxypolyethyleneglycolamine750
METHOXYPOLYOXYETHYLENE AMINE 5,000
mPEG-NH2, 95%, average M.W. 10,000
mPEG-NH2, 95%, average M.W. 20,000
mPEG-NH2, 95%, average M.W. 30,000
mPEG-Amine, 95%, average M.W. 1,000
mPEG-Amine, 95%, average M.W. 2,000
mPEG-Amine, 95%, average M.W. 5,000
METHOXYPOLYETHYLENE GLYCOL AMINE 5,000
Methoxypolyethylene glycol amine 20,000
Poly(ethylene glycol) methyl ether amine
Aminopolyethylene glycol monomethyl ether
mPEG-NH2/ Methoxypolyethylene glycol amine
Methoxypolyethylene glycol amine, M.W. 2000
Methoxypolyethylene glycol amine, M.W. 10000
Methoxypolyethylene glycol amine, M.W. 20000
Methoxypolyethylene glycol aMine, M.W. 5,000
Methoxypolyethylene glycol aMine, M.W. 1,000
AMINOPOLYETHYLENE GLYCOL 750 MONOMETHYL ETHER
O-(2-Aminoethyl)-O'-methylpolyethylene glycol
Methoxypolyethylene glycol aMine, M.W. 13,000
Methoxypolyethylene glycol amine hydrochloride
AMINOPOLYETHYLENE GLYCOL MONOMETHYL ETHER 5,000
AMINOPOLYETHYLENE GLYCOL 2'000 MONOMETHYL ETHER
AMINOPOLYETHYLENE GLYCOL 5,000 MONOMETHYL ETHER
AMINOPOLYETHYLENE GLYCOL 5'000 MONOMETHYL ETHER
Poly(ethylene glycol) α-2-aMinoethyl, ω-Methoxy
mPEG-NH2 · HCl salt, 95%, average Mn: 10,000 Da
M-NH2-5000(METHOXY PEG AMINE, HCL SALT, MW 5000)
alpha-Methyl-omega-aminopoly(oxy-1,2-ethanediyl)
AMINOPOLYETHYLENE GLYCOL 10,000 MONOMETHYL ETHER
AMINOPOLYETHYLENE GLYCOL 10'000 MONOMETHYL ETHER
AMINOPOLYETHYLENE GLYCOL 20,000 MONOMETHYL ETHER
AMINOPOLYETHYLENE GLYCOL 20'000 MONOMETHYL ETHER
O-(2-AMINOETHYL)-O'-METHYLPOLYETHYLENE GLYCOL 750
Poly(ethylene glycol) methyl ether amine (Mn 1000)
O-(2-AMINOETHYL)-O'-METHYLPOLYETHYLENE GLYCOL 5,000
O-(2-AMINOETHYL)-O'-METHYLPOLYETHYLENE GLYCOL 5'000
O-(2-AMINOETHYL)-O'-METHYLPOLYETHYLENE GLYCOL 2'000
O-(2-AMINOETHYL) O'-METHYLPOLYETHYLENE GLYCOL 20'000
O-(2-AMINOETHYL)-O'-METHYLPOLYETHYLENE GLYCOL 20,000
O-(2-AMINOETHYL)-O'-METHYLPOLYETHYLENE GLYCOL 10,000
O-(2-AMINOETHYL)-O'-METHYLPOLYETHYLENE GLYCOL 10'000
polyethylene glycol mono-2-aminoethyl monomethyl ether
Poly(ethylene glycol) methyl ether amine average Mn 500
AMINOPOLYETHYLENE GLYCOL 5'000 MONOMETHYL ETHER ISO 9001:2015 REACH
Methoxypolyethylene glycol aMine 2,000, extent of labeling: >=0.4 MMol/g NH2 loading
Methoxypolyethylene glycol aMine 5,000, extent of labeling: >=0.17 MMol/g NH2 loading
Aminopolyethylene glycol monomethyl ether, Methoxypolyoxyethylene amine, O-(2-Aminoethyl)-Oμ-methylpolyethylene glycol
Methoxypolyethylene glycol amine,O-(2-Aminoethyl)-O′-methylpolyethylene glycol, Aminopolyethylene glycol monomethyl ether, Methoxypolyoxyethylene amine
[Molecular Formula]

H2NCH2CH2(OCH2CH2)nOCH3
[MDL Number]

MFCD00131599
[MOL File]

80506-64-5.mol
[Molecular Weight]

119.162
Chemical PropertiesBack Directory
[Melting point ]

58-61 °C(lit.)
[Fp ]

>110℃
[storage temp. ]

−20°C
[solubility ]

Chloroform (Slightly), MEtanol (Slightly)
[form ]

Granular Solid
[color ]

White to off-white
[Water Solubility ]

Soluble in water.
[α-end]

methoxy
[Ω-end]

amine
[InChI]

InChI=1S/C5H13NO2/c1-7-4-5-8-3-2-6/h2-6H2,1H3
[InChIKey]

QWCGXANSAOXRFE-UHFFFAOYSA-N
[SMILES]

C(N)COCCOC
[EPA Substance Registry System]

Poly(oxy-1,2-ethanediyl), .alpha.-(2-aminoethyl)-.omega.-methoxy- (80506-64-5)
Safety DataBack Directory
[Safety Statements ]

22-24/25
[WGK Germany ]

3
[F ]

2-9
[TSCA ]

Yes
[HS Code ]

39072090
[Storage Class]

10 - Combustible liquids
Hazard InformationBack Directory
[Description]

m-PEG15-amine is a PEG linker containing an amino group and 15 PEG units. It is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydrophilic PEG spacer increases solubility in aqueous media.
[Uses]

MPEG-NH2 is a reactant in synthesis of pH-sensitive polymeric micelles for intracellular drug delivery.
[Application]

Methoxypolyethylene glycol amine is used in the reduction of immunogenicity and increasing serum half life.Methoxypolyethylene glycol amine can:
Form dendritic micelles to enhance the solubility of hydrophobic compounds.
Conjugate with an anticancer drug methotrexate (MTX) to form MTX-PEG with potential application as drug carriers.
Couple with polyethylenimine (PEI) to form graft copolymers which can be used as nonviral gene vectors.
PEG functionalized with amine for ligation and coupling reactions.
[reaction suitability]

reagent type: chemical modification reagent
reactivity: carboxyl reactive
[Synthesis]

1. Preparation of methoxy polyethylene glycol amine 2000

2g of monomethoxy polyethylene glycol azide 2000 was dissolved in 20mL of dry tetrahydrofuran, followed by the addition of 10% palladium carbon 0.2g, the air in the reaction flask was rep

Spectrum DetailBack Directory
[Spectrum Detail]

Methoxypolyethylene glycol amine(80506-64-5)1HNMR
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