| Identification | Back Directory | [Name]
AA 863 | [CAS]
80809-95-6 | [Synonyms]
AA 863
2,5-Cyclohexadiene-1,4-dione, 2-(12-hydroxy-5,10-dodecadiyn-1-yl)-5,6-dimethoxy-3-methyl- | [Molecular Formula]
C21H26O5 | [MOL File]
80809-95-6.mol | [Molecular Weight]
358.43 |
| Hazard Information | Back Directory | [Description]
AA 863 is a 5-lipoxygenase inhibitor that has dose-dependent inhibitory effects on proliferation of human glioma cell lines. | [Uses]
AA863 is a 5-lipoxygenase inhibitor with activity in inhibiting the proliferation of human glioma cells. AA863 exhibits significant and dose-dependent inhibitory effects in monolayer cultured glioma cells with an IC50 of 9.0 micromolar[1]. | [References]
[1] Effects of the 5-lipoxygenase inhibitors AA-863 and U-60,257 on human glioma cell lines DOI:10.1016/0952-3278(90)90153-c |
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