| Identification | More | [Name]
4-(DIETHOXYMETHYL)BENZALDEHYDE | [CAS]
81172-89-6 | [Synonyms]
4-(DIETHOXYMETHYL)BENZALDEHYDE
TEREPHTHALALDEHYDE DIETHYL ACETAL
TEREPHTHALALDEHYDE MONO(DIETHYL ACETAL)
TEREPHTHALDEHYDE MONO(DIETHYL ACETAL)
TEREPHTHALDIALDEHYDE MONODIETHYLACETAL
TerephthaldehydeMonoDiethylacetal97%
Terephthaldehyde mono(diethyl acetal), 98+%
Terephthaldialdehyde-monodiethylacetale
Terephthaldehyde monodiethylacetal, stabilized, 97%
Benzaldehyde, 4-(diethoxymethyl)-
Terephthaldialdehyde monodiethylacetal 98%
Terephthaldialdehyd monodiethylacetal
Terephthaldehyde monodiethylacetal, 97%, stabilized | [Molecular Formula]
C12H16O3 | [MDL Number]
MFCD00010217 | [Molecular Weight]
208.25 | [MOL File]
81172-89-6.mol |
| Chemical Properties | Back Directory | [Appearance]
clear colorless to light yellow liquid | [Boiling point ]
89-93 °C (7 mmHg)
| [density ]
1.047 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.506(lit.)
| [Fp ]
>230 °F
| [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [form ]
liquid (clear)
| [color ]
clear deep yellow
| [Water Solubility ]
soluble in alcohol, chlorinated solvents and toluene. Decomposes in water. | [Sensitive ]
Air Sensitive | [BRN ]
4293872 | [InChI]
InChI=1S/C12H16O3/c1-3-14-12(15-4-2)11-7-5-10(9-13)6-8-11/h5-9,12H,3-4H2,1-2H3 | [InChIKey]
HTMXMFARWHNJDW-UHFFFAOYSA-N | [SMILES]
C(=O)C1=CC=C(C(OCC)OCC)C=C1 | [CAS DataBase Reference]
81172-89-6(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S37/39:Wear suitable gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [F ]
1-10 | [Hazard Note ]
Irritant | [HS Code ]
29124900 |
| Hazard Information | Back Directory | [Chemical Properties]
clear colorless to light yellow liquid | [Uses]
4-(Diethoxymethyl)benzaldehyde was used in the synthesis of 4-(diethoxymethyl)benzyl alcohol. | [Synthesis]
A mixed solution of terephthalaldehyde (10 g, 74.55 mmol) and ammonium chloride (160 mg, 3.0 mmol) in ethanol (10.3 g, 223.6 mmol) was added slowly and dropwise to the reaction flask at 0 °C. Subsequently, triethyl orthoformate (12.15 g, 82 mmol) was added dropwise to the reaction system. The reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, the mixture was concentrated and the residue was purified by silica gel column chromatography to afford the target product terephthalaldehyde diethyl acetal (7.0 g, 50% yield) as a white solid.LC-MS (ESI) m/z: 209 (M + 1)+. | [References]
[1] Patent: US2010/35883, 2010, A1. Location in patent: Page/Page column 91
[2] Patent: WO2011/130661, 2011, A1. Location in patent: Page/Page column 178
[3] Journal of Enzyme Inhibition and Medicinal Chemistry, 2019, vol. 34, # 1, p. 204 - 218 |
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