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81794-13-0

81794-13-0 Structure

81794-13-0 Structure
IdentificationBack Directory
[Name]

2'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine
[CAS]

81794-13-0
[Synonyms]

5'-O-DMT-2'-O-TBDMS adenosine
2'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine
5'-O-(4,4'-DiMethoxytrityl)-2'-O-t-butyldiMethylsilyl adenosine
5'-O-(4,4'-dimethoxytrityl)-2'-O-(tert-butyldimethylsilyl)adenosine
5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]adenosine
Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimet hylsilyl]-
ADENOSINE, 5'-O-[BIS(4-METHOXYPHENYL)PHENYLMETHYL]-2'-O-[(1,1-DIMETHYLETHYL)DIMETHYLSILYL]- (9CI)
[Molecular Formula]

C37H45N5O6Si
[MDL Number]

MFCD20134039
[MOL File]

81794-13-0.mol
[Molecular Weight]

683.87
Hazard InformationBack Directory
[Uses]

5’-O-(4,4’-Dimethoxytrityl)-2’-O-t-butyldimethylsilyl adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
[References]

[1] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020
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