| Identification | Back Directory | [Name]
2,3,5,4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucoside | [CAS]
82373-94-2 | [Synonyms]
THSG
EH-201
EH-201/THSG
CHEMBL460860
Astragalus polyphenols
Tetrahydroxystilbene glucoside
2,3,5,4-Tetrahydroxyl-diphenyl
2,3,5,4'-tetrahydroxystilbene-2
2,3,4,5-Tetrahydroxystilbene 2-glucoside
4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucoside
2,3,4',5-Tetrahydroxystilbene 2-O-Glucoside
2,3,4',5-Tetrahydroxystilbene 2-O-D-glucoside
2,3,5,4′-Tetrahydroxystilbene 2-O-β-D-glucoside
2,3,5,4'-Tetrahydroxy stilbene 2-Ο-β-D-glucoside
2,3,5,4' -tetrahydroxystibene -2-O-β-D –glucoside
2,3,5,4'-tetera-hydroxystilbene-2-O-β-D-glucoside
2,3,5,4-tetrahydroxyl diphenylethylene-2-o-glucosi
2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucopyranosid
2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucopyranosid
2,3,5,4'-Tetrahydroxystilbene-2-O-beta-D-glucopyranoside
2,3,5,4＇-Tetrahydroxy stilbene-2-Ο-β-D-glucoside USP/EP/BP
82373-94-2 2,3,5,4-tetrahydroxyl diphenylethylene-2-o-glucoside
2,3,5,4-tetrahydroxyl diphenylethylene-2-o-glucoside 82373-94-2
2,4-Dihydroxy-6-[(E)-2-(4-hydroxyphenyl)vinyl]phenyl beta-D-Glucopyranoside
2,4-Dihydroxy-6-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenyl β-D-Glucopyranoside
b-D-Glucopyranoside,2,4-dihydroxy-6-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenyl
β-D-Glucopyranoside, 2,4-dihydroxy-6-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenyl
2,4-Dihydroxy-6-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenyl beta-D-Glucopyranoside
2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside, 98%, from Fallopia multiflora (Thunb.) Harald.
2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside (2,3,4',5-Tetrahydroxystilbene 2-O-D-glucoside)
(2S,3R,4S,5S,6R)-2-(2,4-dihydroxy-6-((E)-4-hydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
(2S,3R,4S,5S,6R)-2-[2,4-dihydroxy-6-[(E)-2-(4-hydroxyphenyl)vinyl]phenoxy]-6-(hydroxymethyl)tetrahydropyran-3,4,5-triol | [EINECS(EC#)]
683-231-5 | [Molecular Formula]
C20H22O9 | [MDL Number]
MFCD00238694 | [MOL File]
82373-94-2.mol | [Molecular Weight]
406.38 |
| Chemical Properties | Back Directory | [Boiling point ]
715.0±60.0 °C(Predicted) | [density ]
1.593±0.06 g/cm3(Predicted) | [storage temp. ]
?20°C | [solubility ]
H2O: soluble5mg/mL, clear (warmed) | [form ]
powder | [pka]
8.78±0.40(Predicted) | [color ]
white to brown | [Water Solubility ]
H2O: 5mg/mL, clear (warmed) | [InChI]
InChI=1/C20H22O9/c21-9-15-16(25)17(26)18(27)20(28-15)29-19-11(7-13(23)8-14(19)24)4-1-10-2-5-12(22)6-3-10/h1-8,15-18,20-27H,9H2/b4-1+/t15-,16-,17+,18-,20+/s3 | [InChIKey]
JAYVHSBYKLLDJC-BGLDUWRXNA-N | [SMILES]
O([C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)C1C(=CC(O)=CC=1/C=C/C1C=CC(O)=CC=1)O |&1:1,2,3,5,7,r| | [CAS DataBase Reference]
82373-94-2 |
| Hazard Information | Back Directory | [Description]
2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside is derived from the root of Polygonaceae species Polygonum multiflorum and is a stilbene compound. It has antioxidant, hypotensive, anti-aging, anti-inflammatory, hypolipidemic, cardioprotective and neuroprotective effects. It can also inhibit the formation of 5-HETE, HHT and thromboxane B2. | [Chemical Properties]
Off-white crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Polygonum multiflorum. | [Uses]
2,?3,?4'',?5-?Tetrahydroxystilbene 2-?O-?Glucoside is a scavenging agent, that attenuates free radicals and upregulate antioxidant?/detoxifying enzymes to protect against oxidative damage. It also protects UB?/OC-?2 cells from H2O2-?induced autophagy and apoptosis in vitro. | [Definition]
ChEBI: (E)-2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside is a stilbenoid that is trans-stilbene which has been substituted by hydroxy groups at positions 2, 3, 5, and 4', and in which the hydroxy group at positon 2 has then been converted to the corresponding the beta-D-glucoside. It has a role as an antioxidant, a cyclooxygenase 2 inhibitor, an anti-inflammatory agent, a cardioprotective agent, a platelet aggregation inhibitor and an apoptosis inhibitor. It is a stilbenoid, a beta-D-glucoside and a member of resorcinols. | [General Description]
2,3,5,4′ -Tetrahydroxystilbene-2-O-beta-glucoside (THSG) is a Polygoni Multiflori based polyphenol. | [Biochem/physiol Actions]
2,3,5,4′-Tetrahydroxystilbene 2-O-β-D-glucoside induces the expression and enhances the activity of EPO. The compound stimulates mitochondrial biogenesis, and expression of hemoglobin in non-hematopoietic cells. 2,3,5,4′-Tetrahydroxystilbene 2-O-β-D-glucoside has demonstrated protective effects in cardiovascular disease and ischemia models. | [Physiological effects]
Stilbene glycosides have the functions of brain protection, free radical scavenging, blood lipid lowering, liver protection, anti-tumor, vasodilation, and inhibition of atherosclerosis. |
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