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82572-04-1

82572-04-1 Structure

82572-04-1 Structure
IdentificationBack Directory
[Name]

(R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride
[CAS]

82572-04-1
[Synonyms]

CicalcetImpurity33HCl
Cinacalcet Impurity 33 HCl
(R)-(+)-1,1-Naphthyl ethylamine HCI
(R)-(+)-1-(1-Naphthyl)ethylamine Hcl
(R)-<1-(1-Naphthyl)ethyl>ammonium chloride
(1R)-1-(1-naphthyl)ethanamine hydrochloride
(1R)-1-(1-Naphthyl)ethylamine Hydrochloride
-(+)-1-(1-NAPHTHYL)ETHYLAMINE HYDROCHLORIDE
?-(+)-1-(1-NAPHTHYL)ETHYLAMINE HYDROCHLORIDE
(R)-(+)-1-(1-NAPHTHYL)ETHYLAMINE HYDROCHLORIDE
(1R)-(+)-(1-Naphthyl) ethylamine Hydrochloride
(R)-(+)-alpha-(1-Naphthyl)ethylaminehydrochloride
(R)-1-(naphthalen-1-yl)ethanaMine (Hydrochloride)
(R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride 97%
Cinacalcet Impurity 33 HClCinacalcet Impurity B HCl
(R)-1-(7,8-dihydronaphthalen-1-yl)ethanamine hydrochloride
TIANFU CHEM (R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride
(R)-1-(7,8-dihydrophthalen-1-yl)ethan-1-amine hydrochloride
(R)-1-(7,8-dihydronaphthalen-1-yl)ethan-1-amine hydrochloride
-(+)-1-(1-NAPHTHYL)ETHYLAMINE HYDROCHLORIDE ISO 9001:2015 REACH
1-Naphthalenemethanamine, alpha-methyl-, hydrochloride, (alphaR)-
[EINECS(EC#)]

617-358-4
[Molecular Formula]

C12H14ClN
[MDL Number]

MFCD07369798
[MOL File]

82572-04-1.mol
[Molecular Weight]

207.699
Chemical PropertiesBack Directory
[Melting point ]

253-257 °C(lit.)
[storage temp. ]

Sealed in dry,Room Temperature
[form ]

solid
[Appearance]

White to off-white Solid
[Optical Rotation]

[α]/D 5.2±2°, c = 1 in methanol
[InChI]

InChI=1/C12H13N.ClH/c1-9(13)11-8-4-6-10-5-2-3-7-12(10)11;/h2-9H,13H2,1H3;1H/t9-;/s3
[InChIKey]

ZTNKTVBJMXQOBQ-OVMXBOEKNA-N
[SMILES]

C1(=CC=CC2C=CC=CC1=2)[C@@H](C)N.Cl |&1:10,r|
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)Environment (GHS09)
GHS07,GHS09
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335-H400
[Precautionary statements ]

P261-P273-P305+P351+P338
[Hazard Codes ]

Xn,N
[Risk Statements ]

22-36/37/38-50
[Safety Statements ]

26-60-61
[RIDADR ]

UN 3077 9 / PGIII
[WGK Germany ]

2
[REACH Registrations]

Active
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Acute Tox. 4 Oral
Aquatic Acute 1
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Hazard InformationBack Directory
[Uses]

(R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride is a pharmaceutical intermediate used in the preparation of cinacalcet hydrochloride, which treats secondary hyperparathyroidism due to chronic kidney disease. In addition, (R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride is also used in analytical assays. Absolute configuration of primary amines determined using chiral (2-nitrophenyl)proline amides and 1H NMR.
Spectrum DetailBack Directory
[Spectrum Detail]

(R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride(82572-04-1)1HNMR
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