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827031-83-4

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827031-83-4 Structure

827031-83-4 Structure
IdentificationBack Directory
[Name]

Verubulin
[CAS]

827031-83-4
[Synonyms]

MPC-6827
Verubulin
MX 128495
N-(4-Methoxyphenyl)-N,2-dimethyl-4-quinazolinamine
N-(4-Methoxyphenyl)-N,2-diMethylquinazolin-4-aMine
4-QuinazolinaMine,N-(4-Methoxyphenyl)-N,2-diMethyl-
(4-Methoxyphenyl)(methyl)(2-methylquinazolin-4-yl)amine
[Molecular Formula]

C17H17N3O
[MOL File]

827031-83-4.mol
[Molecular Weight]

279.34
Chemical PropertiesBack Directory
[Melting point ]

86-90℃
[Boiling point ]

398.7±38.0 °C(Predicted)
[density ]

1.189
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: 125 mg/mL (447.48 mM)
[form ]

Solid
[pka]

6.33±0.50(Predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

Verubulin (MPC-6827) is a microtubule-disrupting agent with potent and broad-spectrum in vitro and in vivo cytotoxic activities, and acts as a promising candidate for the treatment of multiple cancer types[1].
[storage]

Store at -20°C
[References]

[1] Kasibhatla S, et al. MPC-6827: a small-molecule inhibitor of microtubule formation that is not a substrate for multidrug resistance pumps. Cancer Res. 2007 Jun 15;67(12):5865-71. DOI:10.1158/0008-5472.CAN-07-0127
Spectrum DetailBack Directory
[Spectrum Detail]

Verubulin(827031-83-4)1HNMR
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