| Identification | Back Directory | [Name]
Verubulin | [CAS]
827031-83-4 | [Synonyms]
MPC-6827
Verubulin
MX 128495
N-(4-Methoxyphenyl)-N,2-dimethyl-4-quinazolinamine
N-(4-Methoxyphenyl)-N,2-diMethylquinazolin-4-aMine
4-QuinazolinaMine,N-(4-Methoxyphenyl)-N,2-diMethyl-
(4-Methoxyphenyl)(methyl)(2-methylquinazolin-4-yl)amine | [Molecular Formula]
C17H17N3O | [MOL File]
827031-83-4.mol | [Molecular Weight]
279.34 |
| Chemical Properties | Back Directory | [Melting point ]
86-90℃ | [Boiling point ]
398.7±38.0 °C(Predicted) | [density ]
1.189 | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 125 mg/mL (447.48 mM) | [form ]
Solid | [pka]
6.33±0.50(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
Verubulin (MPC-6827) is a microtubule-disrupting agent with potent and broad-spectrum in vitro and in vivo cytotoxic activities, and acts as a promising candidate for the treatment of multiple cancer types[1]. | [storage]
Store at -20°C | [References]
[1] Kasibhatla S, et al. MPC-6827: a small-molecule inhibitor of microtubule formation that is not a substrate for multidrug resistance pumps. Cancer Res. 2007 Jun 15;67(12):5865-71. DOI:10.1158/0008-5472.CAN-07-0127 |
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| Company Name: |
Heterochem
|
| Tel: |
027-88041443 13072715837 |
| Website: |
www.hetero-chem.com |
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