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828247-65-0

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828247-65-0 Structure

828247-65-0 Structure
IdentificationBack Directory
[Name]

Adenosine, N-acetyl-3',5'-O-[1,1,3,3-tetrakis(1-Methylethyl)-1,3-disiloxanediyl]-
[CAS]

828247-65-0
[Synonyms]

3',5'-TIPS-N-Ac-
3',5'-TIPS-Ac-rA
N6-Ac-3',5'-TIPDS-Ar
3',5'-TIPS-N-Ac-Adenosine
N6-Acetyl-3',5'-O-TIPDSadenosine
5',3'-tetraisopropyl disiloxane-riboadenosine(N-acetyl)
N6-acetyl-3',5'-O-(Tetraisopropyldisiloxane-1,3-diyl)-adenosine
N-Acetyl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)adenosine
N-Acetyl-3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]adenosine
N6-Acetyl-3’,5’-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]adenosine
Adenosine, N-acetyl-3',5'-O-[1,1,3,3-tetrakis(1-Methylethyl)-1,3-disiloxanediyl]-
[Molecular Formula]

C24H41N5O6Si2
[MDL Number]

MFCD28016486
[MOL File]

828247-65-0.mol
[Molecular Weight]

551.78
Chemical PropertiesBack Directory
[density ]

1.29±0.1 g/cm3(Predicted)
[pka]

9.43±0.43(Predicted)
Hazard InformationBack Directory
[Uses]

3',5'-TIPS-N-Ac-Adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
[References]

[1] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020
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