| Identification | Back Directory | [Name]
ECHINACOSIDE | [CAS]
82854-37-3 | [Synonyms]
beta-d-e
Echicoside
ECHINACOSIDE
Purpureaside C
ECHINACOSIDE(AHP)
Cistanche tubulosa
Echinacoside/CH80711
Echinacoside/CH54339
Echinacoside Standard
ECHINACOSIDE WITH HPLC
ECHINACOSIDE(AMERICAN HERBAL PHARMACOPOEIA)
ECHINACOSIDE 20% DESERTLIVING CISTANCHE P.E.
Echinacoside, froM Cistanche deserticola Y.C.Ma
Echinacoside, 98%, from Cistanche deserticola Y.C.Ma
2-(3,4-dihydroxyphenyl)ethylo-6-deoxy-alpha-l-mannopyranosyl-glucopyranosid
(1-3)-o-(beta-d-glucopyranosyl-(1-6))-,4-(3-(3,4-dihydroxyphenyl)-2-propenoat
2-(3,4-Dihydroxyphenyl)ethyl 3-O-(6-deoxy-α-L-mannopyranosyl)-6-O-β-D-glucopyranosyl-4-O-[3-(3,4-dihydroxyphenyl)propenoyl]-β-D-glucopyranoside
β-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl O-6-deoxy-α-L-mannopyranosyl-(1→3)-O-[β-D-glucopyranosyl-(1→6)]-, 4-[3-(3,4-dihydroxyphenyl)-2-propenoate]
[(2R,3R,4R,5R,6R)-6-[2-(3,4-Dihydroxyphenyl)ethoxy]-5-hydroxy-2-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
Echinacoside
[(2R,3R,4R,5R,6R)-6-[2-(3,4-Dihydroxyphenyl)ethoxy]-5-hydroxy-2-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl) | [Molecular Formula]
C35H46O20 | [MDL Number]
MFCD00075695 | [MOL File]
82854-37-3.mol | [Molecular Weight]
786.73 |
| Chemical Properties | Back Directory | [Boiling point ]
1062.7±65.0 °C(Predicted) | [density ]
1.66±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO:60.0(Max Conc. mg/mL);76.26(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:9):0.1(Max Conc. mg/mL);0.13(Max Conc. mM)
DMF:30.0(Max Conc. mg/mL);38.13(Max Conc. mM)
Ethanol:52.5(Max Conc. mg/mL);66.73(Max Conc. mM)
Water:24.36(Max Conc. mg/mL);30.96(Max Conc. mM) | [form ]
powder | [pka]
8.43±0.20(Predicted) | [color ]
White-beige | [BRN ]
4778612 | [Stability:]
Hygroscopic | [InChIKey]
FSBUXLDOLNLABB-ISAKITKMSA-N | [LogP]
0.140 (est) |
| Hazard Information | Back Directory | [Description]
Echinacoside is a phenylethanoid glycoside that has been found in Echinacea and has diverse biological activities.1,2,3,4 It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals (EC50 = 6.6 μM in a cell-free assay).1 Echinacoside (10 μg/ml) inhibits hydrogen peroxide-induced production of reactive oxygen species (ROS) and apoptosis in PC12 cells.2 It reduces increases in plasma alanine aminotransferase (ALT), TNF-α, IL-1β, IL-16, and IL-10 levels and hepatocyte apoptosis induced by LPS/D-galactosamine in a mouse model of acute liver injury when administered at a dose of 60 mg/kg.3 Echinacoside (20 mg/kg per day for 15 days) prevents loss of dopaminergic neurons in the substantia nigra pars compacta and decreases in striatal dopamine and 3,4-dihydroxyphenylacetic acid (DOPAC) levels in a mouse model of MPTP-induced Parkinson''s disease.4 It also improves motor performance in the rotarod test in the same model. | [Chemical Properties]
White powder | [Uses]
Echinacoside Ethanolate is a caffeic acid glycoside, known for its neuroprotective, antiinflammatory and anti-oxidative activities. Also an anti[proliferative towards hypoxia influenced pulmonary artery smooth muscle cells. | [Definition]
ChEBI: Echinacoside is an oligosaccharide. |
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