| Identification | More | [Name]
4-NITROPHENYL ACETATE | [CAS]
830-03-5 | [Synonyms]
4-NITROPHENYL ACETATE
ACETIC ACID 4-NITROPHENYL ESTER
P-ACETOXYNITROBENZENE
P-NITROPHENYL ACETATE
4-Nitrophenylacetat
4-Nitropheyl acetate
Acetic acid, p-nitrophenyl ester
aceticacid,p-nitrophenylester
Essigsαure-4-nitrophenylester
Phenol, p-nitro-, acetate
Phenol,p-nitro-,acetate
p-Nitrobenzene acetate
p-Nitrobenzeneacetate
p-Nitrophenol acetate
p-nitrophenolacetate
p-nitrophenyl
P-NitrophenylAcetateA.R.
PARA-NITROPHENYLACETATE
4-NITROPHENYL ACETATE 98+%
4-Acetoxy-1-nitrobenzene | [EINECS(EC#)]
212-593-5 | [Molecular Formula]
C8H7NO4 | [MDL Number]
MFCD00007326 | [Molecular Weight]
181.15 | [MOL File]
830-03-5.mol |
| Safety Data | Back Directory | [Hazard Codes ]
F,C | [Risk Statements ]
R11:Highly Flammable.
R34:Causes burns. | [Safety Statements ]
S24/25:Avoid contact with skin and eyes .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S16:Keep away from sources of ignition-No smoking . | [WGK Germany ]
3
| [RTECS ]
AJ1150000
| [TSCA ]
Yes | [HS Code ]
29153900 | [Toxicity]
LD50 ivn-mus: 180 mg/kg CSLNX* NX#00217 |
| Hazard Information | Back Directory | [Chemical Properties]
off-white or beige powder | [Uses]
4-Nitrophenyl Acetate have been used as a substrate to study for the enzymatic activity of Carbonic Anhydrase III isolated from bovine skeletal muscle. | [Uses]
4-Nitrophenyl acetate is used with iodoacetic acid for reductive cleavage of methionine-containing peptides. It is also used as a substrate that has been used in assays for esterase and lipase activity. Inorganic complexes have been evaluated for their methanolysis or hydrolysis activity using p-nitrophenyl acetate. | [Definition]
ChEBI: An acetate ester resulting from the formal condensation of the hydroxy group of 4-nitrophenol with the carboxy group of acetic acid. | [Synthesis Reference(s)]
Synthesis, p. 991, 1981 DOI: 10.1055/s-1981-29674 | [Safety Profile]
Poison by intravenous route. Whenheated to decomposition it emits toxic fumes of NOx. | [Purification Methods]
Recrystallise the ester from absolute EtOH [Moss et al. J Am Chem Soc 108 5520 1986]. [Beilstein 6 IV 1298.] |
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