| Identification | Back Directory | [Name]
Phenol, 3-[4-amino-1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]- | [CAS]
833481-60-0 | [Synonyms]
Phenol, 3-[4-amino-1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]- | [Molecular Formula]
C15H17N5O | [MOL File]
833481-60-0.mol | [Molecular Weight]
283.33 |
| Chemical Properties | Back Directory | [Boiling point ]
535.9±50.0 °C(Predicted) | [density ]
1.34±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
8.99±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Hydroxy-PP is a potent CBR1 inhibitor with an IC50 value of 0.78 μM. Hydroxy-PP also potently inhibits the cytoplasmic tyrosine kinase Fyn with an IC50 value of 5 nM[1]. | [References]
[1] Tanaka M, et al. An unbiased cell morphology-based screen for new, biologically active small molecules. PLoS Biol. 2005 May;3(5):e128. DOI:10.1371/journal.pbio.0030128 |
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