83400-91-3

100-79-8

83400-91-3

An aqueous solution (100 mL) of potassium permanganate (17.95 g, 113.59 mmol) was slowly added dropwise to an aqueous solution (50 mL) containing 2,2-dimethyl-1,3-dioxolane-4-methanol (5.00 g, 37.83 mmol) and potassium hydroxide (2.55 g, 45.45 mmol) at 0 °C. Subsequently, the reaction mixture was stirred at room temperature for about 18 hours. Upon completion of the reaction, the resulting precipitate was collected by filtration and washed with deionized water. The washings were combined with the filtrate and the solvent was removed by vacuum evaporation to afford 2,2-dimethyl-1,3-dioxolane-4-carboxylic acid potassium salt as an extremely hygroscopic white solid (6.50 g, 93% yield). The structure of the product was confirmed by 1H NMR (400 MHz, D2O) δ 1.43 (s, 3H), 1.48 (s, 3H), 3.92-3.98 (m, 1H), 4.27-4.33 (m, 1H), 4.51-4.57 (m, 1H), and mass spectra (MS 145 (M-K)).