| Identification | Back Directory | [Name]
S(-)-ETICLOPRIDE HYDROCHLORIDE | [CAS]
84226-12-0 | [Synonyms]
FLB 131
Eticlopride
s(-)-eticlopride
ETICLOPRIDE HYDROCHLORIDE
S(-)-ETICLOPRIDE HYDROCHLORIDE
3-Chloro-5-ethyl-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-6-hydroxy-2-methoxybenzamide
Benzamide, 3-chloro-5-ethyl-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-6-hydroxy-2-methoxy-
S(-)-3-CHLORO-5-ETHYL-N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]6-HYDROXY-2 METHOXYBENZAMIDE HCL
(-)-3-Chloro-5-ethyl-N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-6-hydroxy-2-methoxybenzamide
S(-)-3-CHLORO-5-ETHYL-N-([1-ETHYL-2-PYRROLIDINYL]METHYL)-6-HYDROXY-2-METHOXYBENZAMIDE HYDROCHLORIDE | [Molecular Formula]
C17H25ClN2O3 | [MDL Number]
MFCD00055132 | [MOL File]
84226-12-0.mol | [Molecular Weight]
340.85 |
| Hazard Information | Back Directory | [Uses]
R (+)-Eticlopride is a dopamine D2-receptor antagonist. | [Definition]
ChEBI:5-chloro-3-ethyl-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-6-methoxybenzamide is a member of salicylamides. | [in vivo]
Eticlopride (10 mg/kg, i.p.) blocks normal vessel morphologyc restored by DA in orthotopic PC3 and HT29 tumor-bearing animals[2].
Eticlopride (0.01 or 0.02 mg/kg, i.p.) alleviates cognitive deficits produced by Quinpirole (HY-B1752) in rats[4].
| Animal Model: | Sprague-Dawley rats treated with Ruinpirole (1 mg/kg) from postnatal days 1 to 21[4] | | Dosage: | 0.01 or 0.02 mg/kg | | Administration: | i.p. | | Result: | Alleviated cognitive deficits produced by neonatal quinpirole treatment in both male and
female rats on the place version of the MWT, as well as in males tested on the match-to-place
version of the MwT (MwT tested on P22 to P28). |
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