| Identification | Back Directory | [Name]
Enoxacin | [CAS]
84294-96-2 | [Synonyms]
Enoxacin sesq
CI-919 hydrate
AT-2266 hydrate
Enoxacin (hydrate)
ENOXACIN SESQUIHYDRATE
EnoxacinSesquihydrate>
Enoxacin hydrate (CI-919)
1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid sesquihydrate
bis(1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-di hydro-1,8-naphthyridine-3-carboxylic acid) trihydrate C30H | [Molecular Formula]
C15H17FN4O3.11/2H2O | [MDL Number]
MFCD01747755 | [MOL File]
84294-96-2.mol | [Molecular Weight]
694.684 |
| Chemical Properties | Back Directory | [Melting point ]
226 °C | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
1 M NaOH: soluble50mg/mL, clear, colorless to faintly yellow | [form ]
neat | [color ]
White to Off-White | [Merck ]
14,3587 | [Stability:]
Hygroscopic | [Major Application]
clinical testing | [InChI]
1S/2C15H17FN4O3.3H2O/c2*1-2-19-8-10(15(22)23)12(21)9-7-11(16)14(18-13(9)19)20-5-3-17-4-6-20;;;/h2*7-8,17H,2-6H2,1H3,(H,22,23);3*1H2 | [InChIKey]
DKNNITGJCMPHKE-UHFFFAOYSA-N | [SMILES]
O.O.O.CCN1C=C(C(O)=O)C(=O)c2cc(F)c(nc12)N3CCNCC3.CCN4C=C(C(O)=O)C(=O)c5cc(F)c(nc45)N6CCNCC6 |
| Hazard Information | Back Directory | [Uses]
antibiotic | [in vivo]
Enoxacin hydrate (Enoxacin sesquihydrate; 100 μM; 2 μl; injected into ear once a day for 3 consecutive days (days 12, 13 and 14)) enhances the the GFP mRNA knockdown efficiency by Lv-siGFP (from 80% to 60%; 40% GFP mRNA level remained), whereas alone has no effect on GFP expression in GFP transgenic line C57BL/6-Tg(ACTB-EGFP)1Osb/J (10 d old) with lentivirus expressing shGFP (Lv-siGFP; injected into ear for 10 days)[3].
| [IC 50]
Quinolone |
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