| Identification | More | [Name]
Boldenone | [CAS]
846-48-0 | [Synonyms]
1,4-ANDROSTADIEN-17BETA-OL-3-ONE
1,4-ANDROSTADIEN-17B-OL-3-ONE
17-BETA-HYDROXY-1,4-ANDROSTADIEN-3-ONE
17BETA-HYDROXYANDROSTA-1,4-DIEN-3-ONE
17B-HYDROXYANDROSTA-1,4-DIEN-3-ONE
17-HYDROXY-10,13-DIMETHYL-6,7,8,9,10,11,12,13,14,15,16,17-DODECAHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE
1-DEHYDROTESTOSTERONE
BOLDENON
BOLDENONE
DELTA-1-TESTOSTERONE
17-beta-hydroxy-17-alpha-1,4-androstadien-3-one
17-beta-hydroxy-androsta-4-dien-3-one
dehydrotestosterone
BOLDENON VETRANAL Packung mit 10 mg
Boldenonebase
ANDROSTA-1,4-DIEN-3-ONE,17-HYDROXY-,(17B)-
(17)-17-Hydroxy-androsta-1,4-dien-3-one
1,2-Dehydrotestosterone
1,2-Didehydrotestosterone
1,4-Androstadien-17-ol-3-one | [EINECS(EC#)]
212-686-0 | [Molecular Formula]
C19H26O2 | [MDL Number]
MFCD00037712 | [Molecular Weight]
286.41 | [MOL File]
846-48-0.mol |
| Chemical Properties | Back Directory | [Appearance]
Crystalline Solid | [Melting point ]
164-166°C | [alpha ]
D25 +25° (in chloroform) | [Boiling point ]
368.77°C (rough estimate) | [density ]
1.0655 (rough estimate) | [refractive index ]
1.4709 (estimate) | [storage temp. ]
Controlled Substance, -20°C Freezer | [solubility ]
DMF: 25 mg/ml; DMSO: 15 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 10 mg/ml | [form ]
A crystalline solid | [pka]
15.05±0.60(Predicted) | [Water Solubility ]
57.1mg/L at 20℃ | [Usage]
Controlled substance. Anabolic steroid | [Major Application]
forensics and toxicology
pharmaceutical (small molecule) | [InChI]
InChI=1/C19H26O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h7,9,11,14-17,21H,3-6,8,10H2,1-2H3/t14-,15-,16-,17-,18-,19-/s3 | [InChIKey]
RSIHSRDYCUFFLA-KRHBYBJCNA-N | [SMILES]
[C@@]12([H])CCC3=CC(=O)C=C[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@H](CC[C@@]21[H])O |&1:0,10,12,16,18,21,r| | [CAS DataBase Reference]
846-48-0(CAS DataBase Reference) | [NIST Chemistry Reference]
Boldenone(846-48-0) |
| Questions And Answer | Back Directory | [Description]
Boldenone is the chemical precursor of its endecylenate ester prodrug boldenone undecylenate – which is used extensively as a steroid for animals, mainly horses and cattle, under the brand name Equipoise, among others. For this application, it is injected to improve the weight, hair coat, appetite, and general physical condition of horses affected by disease, anorexia, or overwork. It is also used as an illegal doping agent for human athletes. As a derivative of testosterone, it retains its anabolic strength, but exhibits reduced androgenic effects.
| [Sources]
https://en.wikipedia.org/wiki/Boldenone_undecylenate
https://en.wikipedia.org/wiki/Boldenone
https://www.drugs.com/vet/equipoise.html
https://www.steroidal.com/steroid-profiles/equipoise/
https://www.evolutionary.org/equipoise-boldenone-undecylenate
|
| Hazard Information | Back Directory | [Chemical Properties]
Crystalline Solid | [Uses]
Boldenone is an anabolic steroid. Controlled substance. | [Uses]
Controlled substance. Anabolic steroid | [Definition]
ChEBI: An 3-oxo-Delta1,Delta4-steroid substituted by an oxo group at position 3 and a beta-hydroxy group at position 17. It is an anabolic androgenic steroid that has been
eveloped for veterinary use. | [Brand name]
Equipoise [Veterinary] (Fort Dodge
Animal Health). | [Synthesis]
Boldenone is obtained by reacting Testosterone with tert-butyldimethylsilyl chloride in the presence of DDQ.
Experimental Procedure: 29.0 g Testosterone was dissolved in 220 ml dioxan/THF 8:2 and cooled to 0°C on ice. After
cooling down a solution of tert-butyldimethylsilyl chloride (46.0 g in 100 ml dioxan/THF 8:2)
was added dropwise and stirred for 90 min at 0°C. Then a suspension of 32.0 g of DDQ in 200
ml dioxan/THF 8:2 was added in 4 equal portions over a period of 4 h. The reaction mixture
was stirred for additional 12 h within coming from 0°C to room temperature.
The resulting suspension was then filtered over Celite and rinsed with 300 ml THF. The filtrate
was evaporated and brown oil was obtained. The oil was diluted in 1500 ml DCM and washed
with 500 ml of 5% aqueous sodium hydroxide. The yellow organic phase was washed with 400
ml water and 400 ml saturated sodium chloride solution, before drying over magnesium sulfate.
After evaporation, the crude product was chromatographed on silica gel by using hexane-ethyl
acetate (3:7), followed by a recrystallization in ethyl acetate. 16.50 g of Boldenone was obtained as
an amber solid (58%). | [References]
[1] C SAUDAN. Testosterone and doping control.[J]. British Journal of Sports Medicine, 2006, 40 Suppl 1: i21-4. DOI: 10.1136/bjsm.2006.027482 |
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