ChemicalBook--->CAS DataBase List--->847225-56-3

847225-56-3

847225-56-3 Structure

847225-56-3 Structure
IdentificationBack Directory
[Name]

2-Cyano-4-fluoropyridine
[CAS]

847225-56-3
[Synonyms]

4-Fluoropicolinonitrile
2-Cyano-4-fluoropyridine
4-fluoropyridine-2-carbonitrile
4-Fluoro-2-pyridinecarbonitrile
2-Pyridinecarbonitrile, 4-fluoro-
2-Cyano-4-fluoropyridine ISO 9001:2015 REACH
2-Cyano-4-fluoropyridine, 4-Fluoropicolinonitrile
[Molecular Formula]

C6H3FN2
[MDL Number]

MFCD09834127
[MOL File]

847225-56-3.mol
[Molecular Weight]

122.1
Chemical PropertiesBack Directory
[Melting point ]

72-74℃
[Boiling point ]

221℃
[density ]

1.24
[Fp ]

88℃
[storage temp. ]

Inert atmosphere,Store in freezer, under -20°C
[form ]

powder
[pka]

-1.44±0.10(Predicted)
[color ]

Yellow
Safety DataBack Directory
[Symbol(GHS) ]

Skull and Crossbones (GHS06)
GHS06
[Signal word ]

Danger
[Hazard statements ]

H301-H311-H331
[Precautionary statements ]

P261-P264-P270-P271-P280-P301+P310+P330-P302+P352+P312-P304+P340+P311-P361-P363-P403+P233-P405-P501
[RIDADR ]

UN3439
[HS Code ]

2933399990
Hazard InformationBack Directory
[Application]

The 2-cyano-4-fluoropyridine is a novel fluorine-containing medical intermediate and has wide application in the field of medicine. 
[Preparation]

(1)4-chloropyridine-2-formamide is prepared by taking 4-chloropyridine-2-methyl formate and ammonia water as raw materials through an ammonolysis reaction; (2) dehydrating 4-chloropyridine-2-formamide under the action of a dehydrating agent to obtain 2-cyano-4-chloropyridine; (3) 2-cyano-4-chloropyridine is subjected to halogen exchange reaction to obtain 2-cyano-4-fluoropyridine.
Spectrum DetailBack Directory
[Spectrum Detail]

2-Cyano-4-fluoropyridine(847225-56-3)1HNMR
2-Cyano-4-fluoropyridine(847225-56-3)19FNMR
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