| Identification | Back Directory | [Name]
[(1R)-2-(4-hydroxyphenyl)-1-[[(1S)-1-[[(2S)-3-methyl-2-methylamino-but anoyl]carbamoyl]-2-phenyl-ethyl]amino]ethyl]phosphonic acid | [CAS]
84890-90-4 | [Synonyms]
I5B1
I5-B1
I5 B1
antibiotic K 4
Antibiotic I5B1
L-Phenylalaninamide, N-methyl-L-valyl-N-[2-(4-hydroxyphenyl)-1-phosphonoethyl]-
Nα-(N-Acetyl-L-isoleucyl)-N-[2-(4-hydroxyphenyl)-1-phosphonoethyl]-L-tyrosinamide
[(1R)-2-(4-hydroxyphenyl)-1-[[(1S)-1-[[(2S)-3-methyl-2-methylamino-but anoyl]carbamoyl]-2-phenyl-ethyl]amino]ethyl]phosphonic acid | [Molecular Formula]
C23H32N3O6P | [MOL File]
84890-90-4.mol | [Molecular Weight]
477.49 |
| Hazard Information | Back Directory | [Description]
Antibiotic K 4 is a novel inhibitor of angiotensin I converting enzyme produced by Actinomadura spiculosospora. | [Uses]
Antibiotic K 4 is an inhibitor of angiotensin I converting enzyme (ACE) (Ki: 0.18 μM). Antibiotic K 4 inhibits pressor response to angiotensin I in rats[1]. | [References]
[1] Koguchi T, et al. K-4, a novel inhibitor of angiotensin I converting enzyme produced by Actinomadura spiculosospora. J Antibiot (Tokyo). 1986 Mar;39(3):364-71. DOI:10.7164/antibiotics.39.364 |
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