| Identification | Back Directory | [Name]
4-CHLORO-5H-PYRROLO[3,2-D] PYRIMIDINE | [CAS]
84905-80-6 | [Synonyms]
SW-58
SWF-58
4-CHLORO-5H-PYRROLO[3
6-chloro-9-deaza-7H-puri
4-Chloro-5H-pyrrolo[3,2-d...
4-chloro-5H-pyrrolo[2,3-c]pyridine
4-Chloro-5H-pyrrol[3,2-d] pyrimidine
5H-Pyrrolo3,2-dpyrimidine, 4-chloro-
4-chloro-1H-pyrrolo[3,2-d]pyriMidine
4-CHLORO-5H-PYROLO-[3,2-d]PYRIMIDINE
4-CHLORO-5H-PYRROLO[3,2-D] PYRIMIDINE
6-chloro-9-deaza-7H-purine, 4-chloro-3H,5H-pyrrolo[3,2-d]pyriMidine, 4-Chloropyrrolo<3,2-d>pyriMidine | [EINECS(EC#)]
632-937-1 | [Molecular Formula]
C6H4ClN3 | [MDL Number]
MFCD06658411 | [MOL File]
84905-80-6.mol | [Molecular Weight]
153.57 |
| Chemical Properties | Back Directory | [Melting point ]
186-188 °C (decomp)(Solv: water (7732-18-5); ethanol (64-17-5)) | [Boiling point ]
325.9±22.0 °C(Predicted) | [density ]
1.531±0.06 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,2-8°C | [pka]
11.58±0.40(Predicted) |
| Hazard Information | Back Directory | [Description]
4-Chloro-5H-pyrrolo[3,2-d]pyrimidine is a purine analog that inhibits the growth of bacteria by binding to the enzyme DNA gyrase. It has been shown to be effective against staphylococcus and Mycobacterium tuberculosis. | [Uses]
4-Chloro-5H-pyrrolo[3,2-d]pyrimidine is a chlorinated pyrrolopyrimidine used in the preparation of compounds with antibacterial and antitumor activities. | [Application]
4-Chloro-5H-pyrrolo[3,2-d]pyrimidine binds to the enzyme DNA gyrase and prevents it from breaking down the bacterial DNA. This drug also has antimycobacterial activity due to its ability to bind to the enzyme RNA polymerase. |
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