| Identification | Back Directory | [Name]
ADL5747 | [CAS]
850176-30-6 | [Synonyms]
ADL5747
ADL 5747; ADL-5747
ADL-5747 free base
ADL-5747 (free base)
ADL 5747 (free base),ADL5747 (free base)
N,N-diethyl-3-hydroxy-4-spiro[chromene-2,4'-piperidine]-4-ylbenzamide
N,N-Diethyl-3-hydroxy-4-(spiro[chromene-2,4'-piperidin]-4-yl)benzamide
Benzamide, N,N-diethyl-3-hydroxy-4-spiro[2H-1-benzopyran-2,4'-piperidin]-4-yl- | [Molecular Formula]
C24H28N2O3 | [MDL Number]
MFCD18633283 | [MOL File]
850176-30-6.mol | [Molecular Weight]
392.49 |
| Hazard Information | Back Directory | [Uses]
ADL-5747 is a selective and orally active agonist of the δ-opioid receptor (DOR). By binding to the δ-opioid receptors, ADL-5747 activates these receptors, thereby playing a role in pain management pathways. ADL-5747 can be used for research into pain management mechanisms[1]. | [References]
[1] Le Bourdonnec B, et al. Spirocyclic delta opioid receptor agonists for the treatment of pain: discovery of N, N-diethyl-3-hydroxy-4-(spiro [chromene-2, 4′-piperidine]-4-yl) benzamide (ADL5747)[J]. Journal of medicinal chemistry, 2009, 52(18): 5685-5702. DOI:10.1021/jm900773n |
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