| Identification | Back Directory | [Name]
1-(Naphthalen-2-yl)-2-(pyrrolidin-1-yl)pentan-1-one hydrochloride | [CAS]
850352-11-3 | [Synonyms]
Energy-1
Naphyrone HCl
Naphyrone (hydrochloride)
b-Naphyrone Hydrochloride
Naphyrone hydrochloride solution
2-Naphthyl Pyrovalerone Hydrochloride
O-2482 Naphthylpyrovalerone or Naphyrone
1-(2-naphthyl)-2-(1-pyrrolidinyl)-1-pentanone
Naphyrone (hydrochloride) (exempt preparation)
1-(naphthalen-2-yl)-2-(pyrrolidin-1-yl)pentan-1-one HCl
1-(2-Naphthalenyl)-2-(1-pyrrolidinyl)-1-pentanone Hydrochloride
1-(Naphthalen-2-yl)-2-(pyrrolidin-1-yl)pentan-1-one hydrochloride
1-(2-naphthalenyl)-2-(1-pyrrolidinyl)-1-Pentanone hydrochloride (1:1)
1-Pentanone, 1-(2-naphthalenyl)-2-(1-pyrrolidinyl)-, hydrochloride (1:1) | [EINECS(EC#)]
200-659-6 | [Molecular Formula]
C19H24ClNO | [MDL Number]
MFCD18379564 | [MOL File]
850352-11-3.mol | [Molecular Weight]
317.853 |
| Chemical Properties | Back Directory | [Melting point ]
>189°C (dec.) | [Fp ]
9℃ | [storage temp. ]
Refrigerator | [solubility ]
Methanol (Slightly) | [form ]
Solid | [color ]
Pale Yellow to Pale Beige | [Major Application]
forensics and toxicology | [InChI]
1S/C19H23NO.ClH/c1-2-7-18(20-12-5-6-13-20)19(21)17-11-10-15-8-3-4-9-16(15)14-17;/h3-4,8-11,14,18H,2,5-7,12-13H2,1H3;1H | [InChIKey]
SIOVYKZRZLWQSY-UHFFFAOYSA-N | [SMILES]
CCCC(N1CCCC1)C(C2=CC(C=CC=C3)=C3C=C2)=O.[H]Cl |
| Safety Data | Back Directory | [Hazard Codes ]
F,T | [Risk Statements ]
11-23/24/25-39/23/24/25 | [Safety Statements ]
7-16-36/37-45 | [RIDADR ]
UN1230 - class 3 - PG 2 - Methanol, solution | [WGK Germany ]
1 | [Storage Class]
3 - Flammable liquids | [Hazard Classifications]
Acute Tox. 3 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Flam. Liq. 2
STOT SE 1 | [DEA Controlled Substances]
CSCN: 1258
CSA SCH: Schedule I
NARC: No |
| Hazard Information | Back Directory | [Description]
Pyrovalerone is a psychoactive compound with stimulatory effects. It is a controlled drug that has been found as a contaminant in products sold as bath salts. Naphyrone (hydrochloride) is an analog of pyrovalerone that is characterized by the substitution of the methylphenyl group of pyrovalerone with a naphthyl group. Naphyrone potently inhibits dopamine, serotonin, and norepinephrine transporters (IC50 = 20, 33, and 136 nM, respectively). Naphyrone, like pyrovalerone, has been detected in bath salt-type products. This compound is intended for forensic and research purposes. | [Chemical Properties]
Pale Yellow Solid | [Uses]
A Pyrovalerone (P997750) analog as selective dopamine transporter inhibitors. | [References]
[1] PETER C. MELTZER. 1-(4-Methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one (Pyrovalerone) Analogues: A Promising Class of Monoamine Uptake Inhibitors[J]. Journal of Medicinal Chemistry, 2006, 49 4: 1420-1432. DOI: 10.1021/jm050797a
[2] LAURIANE TREMEAU-CAYEL . A comparison of single quadrupole mass detection and diode array ultraviolet detection interfaced to ultra-high performance supercritical chromatography for the quantitative analysis of synthetic cathinones[J]. Journal of Chromatography B, 2018, 1091: Pages 96-100. DOI: 10.1016/j.jchromb.2018.05.035 |
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