| Identification | Back Directory | [Name]
3-Chloro-4-fluoro-N-[4-[[2-(phenylcarbonyl)hydrazino]carbonyl]benzyl]benzenesulfonamide | [CAS]
852918-02-6 | [Synonyms]
TCN 201
TCN 201-d5
N-(4-(2-benzoylhydrazinecarbonyl)benzyl)-3-chloro-4-fluorobenzenesulfonaMide
N-[[4-(benzamidocarbamoyl)phenyl]methyl]-3-chloro-4-fluorobenzenesulfonamide
4-[[[(3-Chloro-4-fluorophenyl)sulfonyl]aMino]Methyl]benzoic Acid 2-Benzoylhydrazide
Benzoic acid, 4-[[[(3-chloro-4-fluorophenyl)sulfonyl]amino]methyl]-, 2-benzoylhydrazide
3-Chloro-4-fluoro-N-[4-[[2-(phenylcarbonyl)hydrazino]carbonyl]benzyl]benzenesulfonamide
3-Chloro-4-fluoro-N-[(4-{[2-(phenylcarbonyl)hydrazino]carbonyl}phenyl)methyl]benzenesulfonamide
TCN-201 N-(4-(2-benzoylhydrazinecarbonyl)benzyl)-3-chloro-4-
fluorobenzenesulfonaMide | [Molecular Formula]
C21H17ClFN3O4S | [MDL Number]
MFCD06683895 | [MOL File]
852918-02-6.mol | [Molecular Weight]
461.89 |
| Hazard Information | Back Directory | [Uses]
TCN 201 is a novel NMDA receptor antagonist selective for NR2A- over NR2B-containing receptors. | [Biochem/physiol Actions]
TCN-201 is a sulphonamide derivative, that negatively modulates glycine binding to the GluN1 (glutamate receptor subunit) subunit of the receptor. | [in vivo]
TCN-201 (10 mg/kg; i.p.) is ineffective in CSD blood-oxygen level-dependent (BOLD) response in rats[4]. | [IC 50]
NMDA Receptor | [storage]
Store at -20°C,unstable in solution, ready to use. |
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