| Identification | Back Directory | [Name]
Vetem | [CAS]
85329-89-1 | [Synonyms]
Vetem
Centralvet
Cabergoline diphosphate
Ergoline-8-carboxamide, N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-6-(2-propenyl)-(8-beta)-, phosphate (1:2) | [Molecular Formula]
C26H43N5O10P2 | [MOL File]
85329-89-1.mol | [Molecular Weight]
647.595 |
| Hazard Information | Back Directory | [Uses]
Cabergoline diphosphate is an ergot derived-dopamine D2-like receptor agonist that has high affinity for D2, D3, and 5-HT2B receptors (Ki=0.7, 1.5, and 1.2, respectively). | [References]
[1] Odaka H, et al. Cabergoline, dopamine D2 receptor agonist, prevents neuronal cell death under oxidative stress via reducing excitotoxicity. PLoS One. 2014 Jun 10;9(6):e99271. DOI:10.1371/journal.pone.0099271
[2] Jefferson F, et al. A dopamine receptor d2-type agonist attenuates the ability of stress to alter sleep in mice. Endocrinology. 2014 Nov;155(11):4411-21. DOI:10.1210/en.2014-1134 |
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