| Identification | Back Directory | [Name]
Cediranib Maleate | [CAS]
857036-77-2 | [Synonyms]
AZD 2171 Maleate
Cediranib Maleate
West to Ni BuMa Maleate
Cediranib Maleate(AZD-2171)
AZD-2171 MALEATE;AZD 2171 MALEATE
Cediranib maleate
(AZD-2171 maleate
4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazoline maleate | [Molecular Formula]
C25H27FN4O3·C4H4O4 | [MDL Number]
MFCD27665457 | [MOL File]
857036-77-2.mol | [Molecular Weight]
566.59 |
| Chemical Properties | Back Directory | [Melting point ]
198.3-200.08 °C (polymorph) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO:72.5(Max Conc. mg/mL);127.96(Max Conc. mM)
Water:2.0(Max Conc. mg/mL);3.53(Max Conc. mM) | [form ]
Solid | [color ]
White to off-white | [InChIKey]
JRMGHBVACUJCRP-BTJKTKAUSA-N | [SMILES]
C(/C(=O)O)=C/C(=O)O.O(C1=CC=C2NC(C)=CC2=C1F)C1=NC=NC2C=C(OCCCN3CCCC3)C(OC)=CC1=2 |
| Hazard Information | Back Directory | [Uses]
Cediranib (AZD2171) inhibited VEGF-stimulated proliferation and KDR phosphorylation with IC50 of 0.4 and 0.5 nM, respectively. | [storage]
Store at -20°C |
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