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86-01-1

86-01-1 Structure

86-01-1 Structure
IdentificationBack Directory
[Name]

guanosine 5'-(tetrahydrogen triphosphate)
[CAS]

86-01-1
[Synonyms]

pppG
5'-GTP
Guo-5'-P3
GTP .Free Acid
Guanosine triphosphate
D-Guanosine5'-triphosphate
guanosine triphosphate (-Na2)
-(tetrahydrogen triphosphate)
Guanosine 5'-triphosphoric acid
Guanosine-5'-triphosphate Free acid
guanosine 5'-(tetrahydrogen triphosphate)
guanosine 5'-(tetrahydrogen triphosphate) USP/EP/BP
GTP 100mM Solution (Guanosine-5'-triphosphate, trisodium salt)
[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl (hydroxy-phosphonooxyphosphoryl) hydrogen phosphate
[EINECS(EC#)]

201-647-3
[Molecular Formula]

C10H16N5O14P3
[MDL Number]

MFCD00870880
[MOL File]

86-01-1.mol
[Molecular Weight]

523.18
Chemical PropertiesBack Directory
[density ]

2.75±0.1 g/cm3(Predicted)
[solubility ]

Soluble (water)
[form ]

Liquid
[pka]

pK3:3.0(-2);pk5:7.10(-3);pK6:9.3(-4) (25°C,μ=0.1)
[color ]

Colorless to light yellow
[PH]

7.0 ± 0.1
[Major Application]

pharmaceutical
[InChIKey]

XKMLYUALXHKNFT-UUOKFMHZSA-N
[SMILES]

C(OP(=O)(O)OP(O)(=O)OP(O)(O)=O)[C@H]1O[C@@H](N2C3=C(C(NC(=N3)N)=O)N=C2)[C@H](O)[C@@H]1O
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Sodium hydroxide-->Diethyl ether-->Celite-->Potassium Phosphate Monobasic-->Pectin-->Anion exchange resin,strong basic quarternary ammoniumⅠ-->Adenosine triphosphate-->UTP-->Cytidine triphosphate
Hazard InformationBack Directory
[Chemical Properties]

This product is a white or off-white powder, odorless, hygroscopic, easily soluble in water, insoluble in alcohol and chloroform.
[Uses]

Guanosine 5''-Triphosphate is used in studying the mechanism of action of selected nucleotide analogs. It is used in the screening or evaluating nucleotide-?based drugs targeting SARS-?CoV-?2 RdRp.
[Definition]

ChEBI: GTP is a guanosine 5'-phosphate and a purine ribonucleoside 5'-triphosphate. It has a role as an Escherichia coli metabolite, a mouse metabolite and an uncoupling protein inhibitor. It is a conjugate acid of a GTP(3-).
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