| Identification | More | [Name]
4,7-Dichloroquinoline | [CAS]
86-98-6 | [Synonyms]
4,7-DICHLOROQUINOLINE
4,7-dichloro-quinolin
TL 1473
tl1473
4,7-DICHLOROQUINOLINE, 99+%
4,7-Dichloroquinoline,97%
4,7-DICHLOLROQUINOLINE
4,7-DICHLOROQUINOLINE CHLOROQUINE PHOSPHATE | [EINECS(EC#)]
201-714-7 | [Molecular Formula]
C9H5Cl2N | [MDL Number]
MFCD00006774 | [Molecular Weight]
198.05 | [MOL File]
86-98-6.mol |
| Chemical Properties | Back Directory | [Appearance]
white to light yellow crystal powder | [Melting point ]
81-83 °C (lit.) | [Boiling point ]
298.4 °F (148°C) | [density ]
1.4178 (rough estimate) | [vapor pressure ]
0.103Pa at 25℃ | [refractive index ]
1.6300 (estimate) | [Fp ]
164 °C
| [storage temp. ]
2-30°C | [solubility ]
chloroform: soluble50mg/mL, clear, colorless to greenish-yellow | [form ]
Powder | [pka]
1.99±0.27(Predicted) | [color ]
White to pale brown | [PH]
3.86 (24.9°C) | [biological source]
synthetic | [Water Solubility ]
insoluble | [BRN ]
125359 | [Henry's Law Constant]
2.6×101 mol/(m3Pa) at 25℃, Zhang et al. (2010) | [InChI]
1S/C9H5Cl2N/c10-6-1-2-7-8(11)3-4-12-9(7)5-6/h1-5H | [InChIKey]
HXEWMTXDBOQQKO-UHFFFAOYSA-N | [SMILES]
Clc1ccc2c(Cl)ccnc2c1 | [LogP]
3.193 at 25℃ | [CAS DataBase Reference]
86-98-6(CAS DataBase Reference) | [NIST Chemistry Reference]
Quinoline, 4,7-dichloro-(86-98-6) | [EPA Substance Registry System]
86-98-6(EPA Substance) |
| Safety Data | Back Directory | [Symbol(GHS) ]
 
GHS07,GHS09 | [Signal word ]
Warning | [Hazard statements ]
H315-H317-H319-H411 | [Precautionary statements ]
P261-P264-P273-P280-P302+P352-P305+P351+P338 | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S22:Do not breathe dust . | [WGK Germany ]
3
| [RTECS ]
VB4200000
| [Hazard Note ]
Irritant | [TSCA ]
Yes | [REACH Registrations]
Active | [HS Code ]
29334910 | [Storage Class]
13 - Non Combustible Solids | [Hazard Classifications]
Aquatic Chronic 2
Eye Irrit. 2
Skin Irrit. 2
Skin Sens. 1 |
| Hazard Information | Back Directory | [Chemical Properties]
white to light yellow crystal powder | [Uses]
4,7-Dichloroquinoline is used in the synthesis of hybrid aminoquinoline-triazine derivatives that show anti-microbial activity. In addition, it is used in the synthesis of novel oxazolidinones as anti
-microbial agents showing efficacy against common bacterial strains. Chloroquinoline impurity. | [General Description]
Chloroquine Related Compound A is an impurity of chloroquine, which is a 9-aminoquinoline drug that effectively inhibits viral infections in humans. | [Flammability and Explosibility]
Notclassified | [Synthesis]
4,7-Dichloroquinoline is obtained by chlorination of 7-chloro-4-hydroxyquinoline.
| [Purification Methods]
Crystallise the dichloroquinoline from MeOH or 95% EtOH. [Beilstein 20/7 V 316.] |
|
| Company Name: |
Jinan Wald Chemical Co., Ltd. Gold
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| Telephone: |
0531-88773586 13210588999 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList1770979/0_EN.htm |
| Company Name: |
J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
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| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
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