| Identification | Back Directory | [Name]
quinacainol | [CAS]
86073-85-0 | [Synonyms]
54272RP
PK-10139
RP-54272
1-(4-(2-tert-Butylquinolyl))-3-(4-piperidyl)propanol
2-(1,1-Dimethylethyl)-α-[2-(4-piperidinyl)ethyl]-4-quinolinemethanol
4-Quinolinemethanol, 2-(1,1-dimethylethyl)-α-[2-(4-piperidinyl)ethyl]-
4-Quinolinemethanol, 2-(1,1-dimethylethyl)-alpha-(2-(4-piperidinyl)ethyl)- | [Molecular Formula]
C21H30N2O | [MDL Number]
MFCD00864744 | [MOL File]
86073-85-0.mol | [Molecular Weight]
326.48 |
| Hazard Information | Back Directory | [Description]
Quinacainol is a Class I antiarrhythmic drug. | [Uses]
Quinacainol (PK 10139) is an inhibitor for sodium current with an EC50 of 95 μM. Quinacainol exhibits antiarrhythmic activity by affecting the electrophysiological properties of the heart[1]. | [References]
[1] Rougeot C, et al. PK 10139 and quinidine: interactions with digoxin concentrations in rats and dogs[J]. Journal of pharmacy and pharmacology, 1984, 36(5): 347-349. DOI:10.1111/j.2042-7158.1984.tb04393.x |
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