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862810-50-2

862810-50-2 Structure

862810-50-2 Structure
IdentificationBack Directory
[Name]

Benzeneacetamide, α-ethyl-N-(5-imidazo[1,2-a]pyrimidin-2-yl-2-methylphenyl)-
[CAS]

862810-50-2
[Synonyms]

PVP-037
Benzeneacetamide, α-ethyl-N-(5-imidazo[1,2-a]pyrimidin-2-yl-2-methylphenyl)-
[Molecular Formula]

C23H22N4O
[MOL File]

862810-50-2.mol
[Molecular Weight]

370.45
Chemical PropertiesBack Directory
[density ]

1.19±0.1 g/cm3(Predicted)
[pka]

13.91±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

PVP-037 is a potent TLR7 and TLR8 agonist adjuvant. PVP-037 shows broad innate immune activation and enhances vaccine immune responses [1].
[References]

[1] Soni D, et al. From hit to vial: Precision discovery and development of an imidazopyrimidine TLR7/8 agonist adjuvant formulation. Sci Adv. 2024 Jul 5;10(27):eadg3747. DOI:10.1126/sciadv.adg3747
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