| Hazard Information | Back Directory | [Description]
GSK270822A is a novel selective inhibitor of G protein-coupled receptor kinase 2 (GRK2). | [Uses]
Rho-Kinase-IN-3 (compound 12) is a potent and selective Rho kinase (ROCK1) inhibitor with an IC50 value of 8 nM. Rho-Kinase-IN-3 can be used in research of hypertension[1]. | [References]
[1] Goodman KB, et, al. Development of dihydropyridone indazole amides as selective Rho-kinase inhibitors. J Med Chem. 2007 Jan 11;50(1):6-9. DOI:10.1021/jm0609014 |
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